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TranscriptomicsChanges in gene expression from postnatal (3 wk and 4 wk) to young adult (8 wk) male and female mouse liver (Mus musculus)
Microarray analysis of male and female CD-1 mouse liver was carried out at 3, 4, and 8 wk of age to elucidate developmental changes in gene expression from the pre-pubertal period to young adulthood. A large number of sex-biased and sex-independent genes showed significant changes during this devel...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-34782 | biostudies-arrayexpress
ProteomicsBleomycin model of fibrosis and resolution phase in old and young mice
Bleomycin-induced pulmonary fibrosis in mice mimics major hallmarks of idiopathic pulmonary fibrosis, yet in this model it spontaneously resolves over time. We studied molecular mechanisms of fibrosis resolution and lung repair, focusing on transcriptional and proteomic signatures and the effect of ...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-09 | PXD041050 | Pride
Bleomycin Dia Mouse Lung Fibrosis Age 
UnknownAdolescent, Parent, and Provider Perceptions of a Predictive Algorithm to Identify Adolescent Suicide Risk in Primary Care.
Not available
S-EPMC11056301 | biostudies-literature
ProteomicsBleomycin model of fibrosis and resolution phase in old and young mice
Bleomycin-induced pulmonary fibrosis in mice mimics major hallmarks of idiopathic pulmonary fibrosis, yet in this model it spontaneously resolves over time. We studied molecular mechanisms of fibrosis resolution and lung repair, focusing on transcriptional and proteomic signatures and the effect of ...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-10 | PXD040530 | Pride
Bleomycin Dia Mouse Lung Fibrosis Age 
TranscriptomicsThe Hydra magnipapillata head regeneration transcriptome
Hydra has long been studied for its remarkable ability to regenerate its head. Previous studies focusing on molecular mechanisms of axial patterning and head regeneration using a candidate gene approach have revealed a central role for the canonical Wnt pathway. We performed a global gene expression...
ORGANISM(S): Hydra vulgaris 
2014-12-13 | E-GEOD-64127 | biostudies-arrayexpress
TranscriptomicsResponse to drought and salt stress in leaves of poplar (Populus alba M-CM-^W P. glandulosa): Expression profiling by oligonucleotide microarray analysis
We performed that comprehensive identification of genes responsible for stress tolerance by analyzing the whole-genome expression profiles of poplar (Populus alba M-CM-^W P. glandulosa) leaves exposed to drought and salt stresses. Examination at the molecular level how this tree species responds to ...
ORGANISM(S): Populus alba x Populus glandulosa 
2014-08-12 | E-GEOD-60311 | biostudies-arrayexpress
TranscriptomicsJuvenile obesity in Ossabaw swine produces artery-specific transcriptional changes
We adopted a transcriptome-wide microarray analysis approach to determine the extent to which vascular gene expression is altered as a result of juvenile obesity and identify obesity-responsive mRNAs. We examined transcriptional profiles in the left anterior descending coronary artery (LAD), perivas...
ORGANISM(S): Sus scrofa 
2013-05-29 | E-GEOD-41636 | biostudies-arrayexpress
TranscriptomicsWhole genome microRNA expression profiling of long-lived daf-2(e1370) mutant in C. elegans at young adult stage
In order to get an insight into the complex interplay of miRNAs in insulin signaling, we profiled the small RNA polulation of daf-2(e1370) worms at young adult stage by Next Generation sequencing. We performed Next Generation sequencing to compare miRNA profiles of wild-type and long-lived daf-2(e13...
ORGANISM(S): Caenorhabditis elegans 
2014-11-27 | E-GEOD-61112 | biostudies-arrayexpress
TranscriptomicsHigher maternal folic acid during gestation dysregulates expression of several genes in mice offspring cerebellum
Maternal vitamins and micronutrients during gestational periods have profound impact on the developmemt of newborns as well as influence susceptibility to chronic conditions. Folic acid is indicated to women during pregnancies to prevent occurrence of neural tube defects in infants. Recently, eviden...
ORGANISM(S): Mus musculus 
2015-01-26 | E-GEOD-60531 | biostudies-arrayexpress
GenomicsNucleosome occupancy profiles in young and old mouse liver [MNase-Seq]
Aging is accompanied by physiological impairments, which, in insulin-responsive tissues, including the liver, predispose individuals to metabolic disease. However, the molecular mechanisms underlying these changes remain largely unknown. Here, we analyze genome-wide profiles of RNA and chromatin org...
ORGANISM(S): Mus musculus 
2014-10-23 | E-GEOD-58005 | biostudies-arrayexpress
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