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TranscriptomicsTranscription profiling of human T-ALL cell cultures treated with Compound E, a gamma-secretase inhibitor or vehicle only (DMSO) for 24 h
The NOTCH1 signaling pathway directly links extracellular signals with transcriptional responses in the cell nucleus and plays a critical role during T-cell development and in the pathogenesis over 50% of human T-cell lymphoblastic leukemia (T-ALL) cases. However, little is known about the transcrip...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5827 | biostudies-arrayexpress
ProteomicsmLST8-CCT DSS crosslinking mass spectrometry
DSS crosslinking of mLST8-CCT purified from HEK293T cells using a tandem affinity approach. First cell extract was run over HisTrap column then a streptactin column.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-22 | MSV000083839 | MassIVE
TranscriptomicsGenome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis
In this study we have combined RNA-seq analysis of genome-wide transcriptional start sites with regular RNA-seq to study the transcriptional landscape of Mycobacterium tuberculosis during exponential culture and growth arrest using a starvation model where exponentially growing cells are incubated i...
ORGANISM(S): Mycobacterium tuberculosis 
2013-11-22 | E-MTAB-1616 | biostudies-arrayexpress
GenomicsGenomic mapping of cAMP receptor protein binding in relation to transcriptional start sites in Mycobacterium tuberculosis
In this study we have used ChIPseq analysis to perform comprehensive mapping of the binding profile of the cAMP receptor protein (CRPMt) of M. tuberculosis combined with RNAseq studies to further investigate the transcriptional response following crp gene deletion and under alternative growth condi...
ORGANISM(S): Mycobacterium tuberculosis 
2014-06-24 | E-MTAB-2390 | biostudies-arrayexpress
TranscriptomicsTime course RNA-seq of Mycobacterium tuberculosis exposed to nitric oxide.
Mycobacterium tuberculosis is an intracellular human pathogen with the ability to resist and adapt to many adverse conditions it encounters upon infection. Among these, overcoming the production of nitric oxide by macrophages could be key for M. tuberculosis success. We have challenged M. tuberculo...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2017-08-29 | E-MTAB-5557 | biostudies-arrayexpress
UnknownFirst Paleogenetic Evidence of Probable Syphilis and Treponematoses Cases in the Brazilian Colonial Period.
Not available
S-EPMC6199871 | biostudies-literature
TranscriptomicsInducible expression of HigB toxin in Mycobacterium tuberculosis results in growth inhibition, reduced abundance of a subset of mRNAs and cleavage of tmRNA
In this study RNA-seq analysis of M. tuberculosis H37Rv overexpressing HigB compared to the empty vector control strain has been performed in order to investigate the role of the HigB toxin
ORGANISM(S): Mycobacterium tuberculosis 
2013-09-16 | E-MTAB-1667 | biostudies-arrayexpress
UnknownTitle X Improved Access To Most Effective And Moderately Effective Contraception In US Safety-Net Clinics, 2016-18.
Not available
S-EPMC10033226 | biostudies-literature
ProteomicsBBSome Core Complex
Chemical crosslinking coupled with mass spectrometry data for the BBSome Core Complex
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-22 | MSV000081472 | MassIVE
ProteomicsM.tuberculosis - Whole organism, Pepxml, SC (Cortes,cell_rep,2013)
abundance based on Spectral counting, pepxml, Interaction consistency score: 5.2, Coverage: 36
ORGANISM(S): 83332 
2013-00-00 | 853879106 | PAXDB
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