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TranscriptomicsTranscription profiling of mouse cartilage tumours IGFBP-3 reveals is regulated by Gli signaling in cartilage tumors.
Mice that develop benign cartilage lesions due to overexpression of Gli2 in chondrocytes developed lesions similar to chondrosarcomas when also deficient in p53. Gli2 overexpression and p53 deficiency had opposing effects on chondrocyte differentiation, but had additive effects negatively regulatin...
ORGANISM(S): Mus musculus 
2009-03-14 | E-GEOD-15118 | biostudies-arrayexpress
UnknownTherapeutic potential of SGN-CD19B, a PBD-based anti-CD19 drug conjugate, for treatment of B-cell malignancies.
Not available
S-EPMC5669207 | biostudies-literature
UnknownLenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis.
Not available
S-EPMC5652871 | biostudies-literature
MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
UnknownSoluble ST2 Is a Sensitive and Specific Biomarker for Fulminant Myocarditis.
Not available
S-EPMC9075487 | biostudies-literature
UnknownTuning ion correlations at an electrified soft interface.
Not available
S-EPMC3528511 | biostudies-literature
TranscriptomicsKras G12D Mutant vs. Wildtype
The experiment is a study of the effects of signal strength in the Ras pathway. In particular, we studied a gain-of-function mutant of Kras, KrasG12D. We generated these mutant mice and performed microarray analyses on RNA extracted from whole skin, comparing KrasG12D mice to wild-type mice, with th...
ORGANISM(S): Mus musculus 
2011-06-03 | E-MTAB-700 | biostudies-arrayexpress
UnknownGene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages.
Not available
S-EPMC5821458 | biostudies-literature
UnknownSenescence-associated lineage-aberrant plasticity evokes T-cell-mediated tumor control.
Not available
S-EPMC11955568 | biostudies-literature
TranscriptomicsExpression data from mouse small intestinal γδ intraepithelial lymphocytes
The mammalian gastrointestinal tract harbors thousands of bacterial species that include symbionts as well as potential pathogens. The immune responses that limit access of these bacteria to underlying tissue remain poorly defined. In this study, we used microarrays to uncover the transcriptional re...
ORGANISM(S): Mus musculus 
2011-04-06 | E-GEOD-28437 | biostudies-arrayexpress
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