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GenomicsGenome-wide mapping of the transcription factor GABP-alpha binding in human CD34+CD133+ hematopoietic progenitor cells.
We used ChIP-Seq to map GABP-alpha binding sites in human hematopoietic progenitor cells (HPCs). Coupled with functional assays using GABP-alpha deficient mouse model and bioinformatics analysis, we systematically determined a transcriptional module controlled by GABP in HPCs. Examination of the rol...
ORGANISM(S): Homo sapiens 
2010-12-10 | E-GEOD-24933 | biostudies-arrayexpress
TranscriptomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b [RNA-Seq]
ES cell pluripotency is thought to be regulated in part by H3K4 methylation. However, it is unclear how H3K4 demethylation contributes to ES cell function and participates in iPS cell reprogramming. Here, we show that KDM5B, which demethylates H3K4, is important for ES cell differentiation, and pres...
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-47124 | biostudies-arrayexpress
TranscriptomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-46893 | biostudies-arrayexpress
GenomicsExtended self-renewal and accelerated reprogramming in the absence of Kdm5b [ChIP-Seq]
ES cell pluripotency is thought to be regulated in part by H3K4 methylation. However, it is unclear how H3K4 demethylation contributes to ES cell function and participates in iPS cell reprogramming. Here, we show that KDM5B, which demethylates H3K4, is important for ES cell differentiation, and pres...
ORGANISM(S): Mus musculus 
2013-10-14 | E-GEOD-47123 | biostudies-arrayexpress
TranscriptomicsExpression and regulation of lincRNAs during T cell development and differentiation
Although lincRNAs are implicated in regulating gene expression in various tissues, little is known about lincRNA transcriptomes in the T cell lineages. Here we identify 1,524 lincRNAs in 42 T cell samples from early T cell progenitors to terminally differentiated T helper subsets. Our analysis revea...
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-48138 | biostudies-arrayexpress
UnknownEffects and mechanisms of trifolin on attenuating hypertension-induced vascular smooth muscle cell proliferation and collagen deposition in vivo and in vitro.
Not available
S-EPMC12062450 | biostudies-literature
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