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UnknownData on solubilization, identification, and thermal stability of human Presenilin-2.
Not available
S-EPMC5852265 | biostudies-literature
TranscriptomicsGene expression data from human metastatic melanoma tumors that may predict response to RAF265
To determine how mutation of BRAF affected the response to RAF265, we utilized a tumor orthotopic implant model of early passage melanoma tumors in nude mice from a series of 17 patients with advanced metastatic Tumor growth was compared between RAF265 treatment (40 mg/kg, QD) and diluent control gr...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-30812 | biostudies-arrayexpress
Proteomics,MultiomicsHs_NSCLC_Phospho
This is a large-scale survey of tyrosine kinase activity in lung cancer. Tyrosine kinase signaling across 41 non-small cell lung cancer (NSCLC) cell lines and over 150 NSCLC tumors are characterized Using a phosphoproteomic approach.
ORGANISM(S): Homo Sapiens (human) 
2007-12-31 | PAe005321 | PeptideAtlas
ProteomicsAstrocyte, OPC, OL in rat postnatal development
Proteomic analysis of astrocyte, OPC, OL isolated from postnatal day 5 rat.
ORGANISM(S): Rattus Norvegicus 
2022-05-03 | PXD033729 |
UnknownSensory neurons promote immune homeostasis in the lung.
Not available
S-EPMC10811756 | biostudies-literature
UnknownBrief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.
Not available
S-EPMC3670944 | biostudies-literature
TranscriptomicsFC-IBC-02: A New in vitro-in vivo Model of Triple Negative Inflammatory Breast Cancer
Inflammatory breast cancer (IBC) is the most aggressive type of advanced breast cancer and is associated with a poor prognosis. We have developed a new model of IBC derivated from the pleural effusion of a 49-year-old woman with metastatic secondary IBC. FC-IBC02 tumor cells were isolated from the p...
ORGANISM(S): Homo sapiens 
2012-09-20 | E-GEOD-40464 | biostudies-arrayexpress
TranscriptomicsTranscriptional dysregulation of synaptic genes in a human iPSC model of major mental disorders
Schizophrenia and other psychiatric disorders are postulated to be developmental disorders resulting from synapse dysfunction. How susceptibility genes for major mental disorders could lead to synaptic deficits in humans is not well-understood. Here we generated induced pluripotent stem cells (iPSCs...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-57821 | biostudies-arrayexpress
ProteomicsDimeric IgA specifically disables intracellular mutated oncodrivers
Despite their long half-life, therapeutic antibodies are considered ineffective against intracellular antigens due to their perceived inability to penetrate epithelial cells. Using recombinant antibodies targeting common mutations in oncogenes, we demonstrate that dimeric IgA, but not the same antib...
ORGANISM(S): Homo Sapiens 
PXD044426 | panorama
GenomicsA Genome-Wide Association Study of Lung Cancer Risk

Three genetic loci for lung cancer risk have been identified by genome-wide association studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well established. We conducted a GWAS of lung cancer and its major histologic types genotyping 515,922 single n...

phs000336.v1.p1 | EGA
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