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ModelsVenkatraman2011 - PLS-UPA behaviour in the presence of substrate competition_1_1_1_1
Venkatraman2011 - PLS-UPA behaviour in the presence of substrate competition The posibility of ultrasensitivity and bistable activation of PLS (Plasmin) and UPA (Urokinase-type plasminogen activator) in the presence of substrate competition is explained here using a mathematical model.  ...
2024-09-02 | BIOMD0000000630 | BioModels
ModelsVenkatraman2012 - Interplay between PLS and TSP1 in TGF-β1 activation
Venkatraman2012 - Interplay between PLS and TSP1 in TGF-β1 activation The interplay between PLS (Plasmin) and TSP1 (Thrombospondin-1) in TGF-β1 (Transforming growth factor-β1)is shown using mathematical modelling and in vitro experimentents. ...
2024-09-02 | BIOMD0000000447 | BioModels
UnknownTrends and Spatial Pattern Analysis of Typhoid and Paratyphoid Fever Incidence - Yunnan Province, China, 1989-2022.
Not available
S-EPMC11532531 | biostudies-literature
UnknownPI3K/AKT/mTOR pathway inhibitors inhibit the growth of melanoma cells with mTOR H2189Y mutations in vitro.
Not available
S-EPMC5989792 | biostudies-literature
TranscriptomicsRNA-seq of human hepatocellular carcinoma cell line Huh7 and immortalized hepatocyte cell line THLE5B treated with experimental compound AD80, Sorafenib, and vehicle for 24 hours
To delineate the transcriptomic changes induced by AD80 relative to sorafenib, we performed RNA-sequencing (RNA-seq) on HUH7 and THLE5B cells treated for 24 hours with either DMSO, sorafenib, or AD80 near respective growth inhibitory GI50 values. HUH7 cells were plated in 6 well plates, treated for ...
ORGANISM(S): Homo sapiens 
2019-08-02 | E-MTAB-7847 | biostudies-arrayexpress
ProteomicsDifferences in gene expression between colony and aggregate biofilms of Clostridioides difficile revealed by proteomic profiling
The protein inventory of the anaerobic pathogen Clostridioides difficile grown in colony or aggregate biofilms was investigated in a comprehensive LC-MS/MS approach. C. difficile has a versatile metabolism and is perfectly equipped to survive and persist inside the mammalian intestine. However, know...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2021-07-12 | PXD022830 | Pride
Rpon signaling Clostridioides difficile Biofilm Persistence Cell surface antigens Lc-ms/ms 
UnknownBrain cellular senescence in mouse models of Alzheimer's disease.
Not available
S-EPMC9135905 | biostudies-literature
TranscriptomicsGene expression analysis of osteosarcoma tumor-initiating cells (High) vs bulk tumor cells (Low)
In the cancer stem cell model a cell hierarchy has been suggested as an explanation for intratumoral heterogeneity, and tumor formation is thought to be driven by this tumor cell subpopulation. The identification of cancer stem cells in osteosarcoma (OS) and the biological processes dysregulated in ...
ORGANISM(S): Homo sapiens 
2011-11-04 | E-GEOD-33458 | biostudies-arrayexpress
UnknownKi67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
Not available
S-EPMC5455353 | biostudies-literature
TranscriptomicsTranscription profiling of yeast homozygous and essential heterozygous diploid deletion strains screened with 3-nitroso-imidazo[1,2-a]pyridines and -pyrimidines to identify gene deletions that confer sensitivity to each compound
The complete pool of barcoded homozygous and essential heterozygous diploid deletion strains of S. cerevisiae were screened with 3-nitroso-imidazo[1,2-a]pyridines and -pyrimidines to identify gene deletions that confer sensitivity to each compound.
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-19 | E-TABM-560 | biostudies-arrayexpress
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