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TranscriptomicsComparative genomic hybridization of 30 ovarian cancer cell lines reveals amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer
DNA from 30 cultured ovarian cancer cell lines was extracted with Promega kits and hybridize to arrays. Arrays comprised of 1860 BACs selected to include genes known to be involved in cancer pathogenesis and 400 BACs selected to tile across 13 Mbp at 3q26, 15 Mbp at 8q24, and 30 Mbp at 20q centered ...
ORGANISM(S): Homo sapiens 
2007-06-04 | E-TABM-246 | biostudies-arrayexpress
TranscriptomicsA sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
Myc is an oncogenic transcription factor frequently dysregulated in human cancer. To identify pathways supporting the Myc oncogenic program, we employed a genome-wide RNAi screen for Myc-synthetic-lethal (MySL) genes and uncovered a role for the SUMO-activating-enzyme (SAE1/2). Loss of SAE1/2 enzyma...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-34055 | biostudies-arrayexpress
GenomicsGenentech_cell_line_SNP
SNP array data for 668 cancer cell lines
EGAD00010000951 | EGA
Genomicsena-DATASET-Genentech-11-09-2014-19:43:22:926-1 - samples
RNAseq and exome sequencing data of gastric cancer cell lines.
EGAD00001001013 | EGA
Genomicsena-DATASET-GENENTECH-24-01-2014-01:33:01:945-58 - samples
This dataset contains RNA sequencing data for 675 cancer cell lines. RNA libraries were made with the TruSeq RNA Sample Preparation kit (Illumina) according to the manufacturer protocol. The libraries were sequenced on an Illumnia HiSeq 2000
EGAD00001000725 | EGA
GenomicsRNA sequencing and Illumina 2.5M SNP array data collected from 675 commonly used human cancer cell lines.
Tumor-derived cell lines have served as vital models to advance our understanding of oncogene function and therapeutic response1. Although substantial effort has been directed to defining the genomic constitution of cancer cell line panels2–4, the transcriptome – which represents the active program ...
EGAS00001000610 | EGA
TranscriptomicsTranscription profiling of human ovarian cancer cell lines
RNA from 30 ovarian cancer lines was extracted when cells were growth to 70-80% confluency. Total RNA was extraced with Qiagen Rneasy columns and evaluated for quality by Bioanalyzer.
ORGANISM(S): Homo sapiens 
2007-06-05 | E-TABM-254 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 675 commonly used human cancer cell lines
Tumor-derived cell lines have served as vital models to advance our understanding of oncogene function and therapeutic response1. Although substantial effort has been directed to defining the genomic constitution of cancer cell line panels24, the transcriptome which represents the active program of...
ORGANISM(S): Homo sapiens 
2014-11-25 | E-MTAB-2706 | biostudies-arrayexpress
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