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TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
ProteomicsC. elegans as a model for inter-individual variation in metabolism
Fox BW, Ponomarova O, Lee YU, Zhang G, Giese EG, Walker M, Roberto NM, Na H, Reis-Rodrigues P, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM (2022) C. elegans as a model for inter-individual variation in metabolism
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2021-07-13 | MSV000087810 | MassIVE
UnknownGlaucoma: Novel antifibrotic therapeutics for the trabecular meshwork.
Not available
S-EPMC10804937 | biostudies-literature
TranscriptomicsGene expression analysis of osteosarcoma tumor-initiating cells (High) vs bulk tumor cells (Low)
In the cancer stem cell model a cell hierarchy has been suggested as an explanation for intratumoral heterogeneity, and tumor formation is thought to be driven by this tumor cell subpopulation. The identification of cancer stem cells in osteosarcoma (OS) and the biological processes dysregulated in ...
ORGANISM(S): Homo sapiens 
2011-11-04 | E-GEOD-33458 | biostudies-arrayexpress
UnknownHuman iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.
Not available
S-EPMC5615077 | biostudies-literature
UnknownMutations in the m-AAA proteases AFG3L2 and SPG7 are causing isolated dominant optic atrophy.
Not available
S-EPMC7251510 | biostudies-literature
UnknownEvaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy.
Not available
S-EPMC5644719 | biostudies-literature
UnknownDeveloping a synergistic rate-retarding polymeric implant for controlling monoclonal antibody delivery in minimally invasive glaucoma surgery.
Not available
S-EPMC11780753 | biostudies-literature
UnknownPattern of retinal ganglion cell loss in dominant optic atrophy due to OPA1 mutations.
Not available
S-EPMC3094220 | biostudies-literature
TranscriptomicsTranscrition profiling of Langerhans Cell Histiocytosis to determine cell specific gene expression
Langerhans-cell histiocytosis (LCH) is characterized by heterogeneous lesions containing CD207+ Langerhans cells (LCs) and lymphocytes. In this study, we isolated CD207+ cells and CD3+ T cells from LCH lesions to determine cell-specific gene expression. Compared to control epidermal CD207+ cells,...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-16395 | biostudies-arrayexpress
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