Sort   by:  
 Page size 
TranscriptomicsCpeb4-mediated Translational Regulatory Circuitry Controls Terminal Erythroid Differentiation
Erythropoiesis is essential to mammals and is regulated at multiple steps by both extracellular and intracellular factors. Many transcriptional regulatory networks in erythroid differentiation have been well characterized. However, our understanding of post-transcriptional regulatory circuitries in ...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-57004 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse primary brown preadipocytes
Brown adipocytes are specialized for heat generation and energy expenditure as a defense against cold and obesity. Recent studies demonstrate that brown adipocytes arise in vivo from a Myf5-positive, myoblastic progenitor by the action of PRDM16. Here, we identified a brown fat-enriched miRNA cluste...
ORGANISM(S): Mus musculus 
2011-05-02 | E-GEOD-27614 | biostudies-arrayexpress
TranscriptomicsESlncRNA (AK148461) over-expression on gene expression
We over-expressed ESlncRNA (AK148461) in fetal liver erythroid progenitor cells (Lin-cells), followed by microarray analysis to examine the global changes of gene expression level. We showed that ESlncRNA has an anti-apoptotic activity during mouse erythropoiesis. Compare the gene expression level i...
ORGANISM(S): Mus musculus 
2012-01-06 | E-GEOD-30279 | biostudies-arrayexpress
TranscriptomicsDe novo Reconstruction of Adipose Tissue Transcriptomes Reveals Novel Long Non-coding RNAs that Regulate Brown Adipocyte Development
Brown adipose tissue (BAT) protects against obesity by promoting energy expenditure via uncoupled respiration. To uncover BAT-specific long non-coding RNAs (lncRNAs), we used RNA-seq to reconstruct de novo transcriptomes of mouse brown, inguinal white, and epididymal white fat and identified ~1500 l...
ORGANISM(S): Mus musculus 
2015-04-23 | E-GEOD-66686 | biostudies-arrayexpress
TranscriptomicsGlobal discovery of erythroid long non-coding RNAs reveals novel regulators of red cell maturation
Erythropoiesis is regulated at multiple levels to ensure the proper generation of mature red cells under multiple physiological conditions. To probe the contribution of long non-coding RNAs (lncRNAs) to this process, we examined >1 billion RNA-Seq reads of polyadenylated and nonpolyadenylated RNA fr...
ORGANISM(S): Mus musculus 
2013-11-07 | E-GEOD-52126 | biostudies-arrayexpress
TranscriptomicsZebrafish promoter microarrays identify actively transcribed embryonic genes
We have designed a zebrafish genomic microarray to identify DNA-protein interactions in the proximal promoter regions of over 11,000 zebrafish genes. Using these microarrays, together with chromatin immunoprecipitation with an antibody directed against tri-methylated lysine 4 of Histone H3, we demon...
ORGANISM(S): Danio rerio 
2010-07-01 | E-GEOD-4863 | biostudies-arrayexpress
Sort   by:  
 Page size