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TranscriptomicsRole of MicroRNA-214 in Ginsenoside-Rg1-induced Angiogenesis
MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional gene modulators. Ginsenoside-Rg1, one of the active components of ginseng, has been confirmed by us as an angiogenesis inducer. Using miRNA microarray analysis, a total of 15 (including miR-214) and 3 miRNAs were found to ...
ORGANISM(S): Homo sapiens 
2010-08-05 | E-GEOD-17541 | biostudies-arrayexpress
TranscriptomicsMicroRNAs expression in 20(R)-ginsenoside Rg3-induced anti-angiogenesis
The angio-suppressive effect of 20(R)-ginsenoside Rg3 (Rg3-R) has been previously demonstrated, and microRNAs (miRNAs) are a vital group of small non-coding RNAs that function as post-transcriptional modulator of gene expression. Thus, using human umbilical vein endothelial cells (HUVEC) as model, w...
ORGANISM(S): Homo sapiens 
2011-09-09 | E-GEOD-31959 | biostudies-arrayexpress
ProteomicsSuccinyl-CoA synthetase deficiency in mouse forebrain results in hyper-succinylation with perturbed neuronal transcriptional regulation and metabolism
Lysine-succinylation is a subtype of protein acylation associated with metabolic regulation of succinyl-CoA in the TCA cycle. Deficiency of succinyl-CoA synthetase (SCS), the TCA-cycle enzyme catalyzing the reversible conversion of succinyl-CoA to succinate, leads to mitochondrial encephalomyopathy ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-06-21 | MSV000089697 | MassIVE
TranscriptomicsDirect calibration of PICKY-designed microarrays
Picky is an optimal microarray design software which designed the NSF Rice 45K Array. A series of microarray experiments using a one-chip version of this array were conducted to validate as well as to develop a calibration method for Picky designed microarrays. Synthesized samples with known content...
ORGANISM(S): synthetic construct 
2010-06-21 | E-GEOD-14717 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression profiling and its integration with mRNA in metastatic melanoma reveal associations with BRAF mutation status and patient prognosis
Objectives/experimental design Samples eligible for this study (n=84) were obtained from lymph node specimens (Melanoma Institute Australia (MIA) Biospecimen Bank) in which macroscopic tumor was observed, obtained from patients believed to be without distant metastases at the time of tumor banking b...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-59334 | biostudies-arrayexpress
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
UnknownBardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease.
Not available
S-EPMC4496027 | biostudies-literature
TranscriptomicsMolecular analysis of gastric cancer identifies discrete subtypes associated with distinct clinical characteristics and survival outcomes: the ACRG (Asian Cancer Research Group) study [gastric tumors]
Gastric cancer, a leading cause of cancer related deaths, is a heterogeneous disease, with little consensus on molecular subclasses and their clinical relevance. We describe four molecular subtypes linked with distinct patterns of molecular alterations, disease progression and prognosis viz. a) Micr...
ORGANISM(S): Homo sapiens 
2015-04-17 | E-GEOD-62254 | biostudies-arrayexpress
UnknownBeyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators.
Not available
S-EPMC12637077 | biostudies-literature
UnknownAcceleration of the loss of the first-phase insulin response during the progression to type 1 diabetes in diabetes prevention trial-type 1 participants.
Not available
S-EPMC3837047 | biostudies-literature
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