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TranscriptomicsExpression profiling of peripheral blood of chronic HCV infection
In the present study, we studied chronic HCV patients who responded to IFN-based therapy as evidenced by absence of HCV RNA at the end of treatment, and focused on two issues that have not received much attention. Firstly, we evaluated whether specific genes or gene expression patterns in blood were...
ORGANISM(S): Homo sapiens 
2014-09-02 | E-GEOD-59312 | biostudies-arrayexpress
TranscriptomicsEarly divergence of Th1 and Th2 transcriptomes involves a small core response and sets of transiently expressed genes
Helper T cells can adopt a number of different phenotypes. We performed microarray-assisted mRNA profiling on antigen-stimulated, TCR transgenic murine splenocytes that were cultured in the presence of cytokines. Transcriptome snapshots of Th cells differentiating into Th1 and Th2 phenotypes were o...
ORGANISM(S): Mus musculus 
2013-03-01 | E-MTAB-1475 | biostudies-arrayexpress
TranscriptomicsNeutrophil extracellular traps and alveolar barrier disruption contribute to varicella pneumonia pathology
Varicella pneumonia is the most common and severe complication of primary varicella-zoster virus (VZV) infection in adults. Pathogenesis of varicella pneumonia is largely unknown, mainly due to limited availability of clinical specimens and lack of appropriate VZV animal models. Simian varicella vir...
ORGANISM(S): Macaca fascicularis 
2020-09-01 | E-MTAB-8485 | biostudies-arrayexpress
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