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MetabolomicsObesogenic high-fat diet and MYC cooperate to promote lactate accumulation and tumor microenvironment remodeling in prostate cancer (Murine serum assays)

Cancer cells exhibit metabolic plasticity to meet oncogene-driven dependencies while coping with nutrient availability. A better understanding of how systemic metabolism impacts the accumulation of metabolites that reprogram the tumor microenvironment and drive cancer could facilitate development...

2024-04-10 | MTBLS3316 | MetaboLights
MetabolomicsObesogenic high-fat diet and MYC cooperate to promote lactate accumulation and tumor microenvironment remodeling in prostate cancer (Murine prostate assays)

Cancer cells exhibit metabolic plasticity to meet oncogene-driven dependencies while coping with nutrient availability. A better understanding of how systemic metabolism impacts the accumulation of metabolites that reprogram the tumor microenvironment and drive cancer could facilitate development...

2024-04-10 | MTBLS3317 | MetaboLights
TranscriptomicsTime-course gene expression data from deletion strains of Penicillium chrysogenum
In filamentous fungi, secondary metabolism is often linked with developmental processes such as conidiation. In this study we analyzed the link between secondary metabolism and conidiation in the main industrial producer of the β-lactam antibiotic penicillin, the ascomycete Penicillium chrysogenum. ...
ORGANISM(S): Penicillium chrysogenum 
2011-01-04 | E-GEOD-23326 | biostudies-arrayexpress
TranscriptomicsTime-course gene expression data from deletion strains of Penicillium chrysogenum
The recent discovery of a velvet complex containing several regulators of secondary metabolism in the model fungus Aspergillus nidulans raises the question whether similar type complexes direct fungal development in genera other than Aspergillus. Penicillium chrysogenum is the industrial producer of...
ORGANISM(S): Penicillium chrysogenum 
2010-06-17 | E-GEOD-18585 | biostudies-arrayexpress
TranscriptomicsRNAs expression profiling in a resistant and a susceptible grapevine cultivar to Plasmopara viticola
Plasmopara viticola (Berk. and Curt.) Berl. and de Toni is the agent of the destructive disease known as grapevine downy mildew, for the control of which intensive fungicide treatments are required. Natural sources of resistance are available in several wild Vitis species, which are being used in tr...
ORGANISM(S): Vitis riparia 
2010-06-24 | E-GEOD-18596 | biostudies-arrayexpress
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