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This study comprises arrayCGH data from the University clinic Eppendorf (UKE) in Hamburg. The array platform being used is the VUMC v30 30k Oligo chip
ORGANISM(S): homo sapiens 
Smoothened (SMO)-inhibitors recently entered clinical trials for sonic-hedgehog driven medulloblastoma (SHH-MB). Clinical response appears highly variable. To understand the mechanism(s) of primary resistance and to identify pathways co-operating with aberrant SHH-signaling, we sequenced a large coh...
ORGANISM(S): Homo sapiens 
This dataset contains paired fastq files for LMS tumor samples
The data set contains paired end fastq files for whole exome sequencing data for Leiomyosarcoma tumor and control samples
The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.
DATA_SET_Coverage_bias_sensitivity_of_variant_calling_for_4_WG_seq_tech
Massively parallel sequencing has revolutionized research in cancer genetics and genomics and enhanced our understanding of natural human genetic variation. Recently, Lam et al. have performed a detailed comparison of two next-generation sequencing technologies with respect to their sensitivity to c...
Leiomyosarcoma (LMS) is an aggressive mesenchmyal malignancy with few therapeutic options. The mechanisms underlying LMS development, including clinically actionable genetic vulnerabilities, are largely unknown. We performed genomic and transcriptomic profiling of a large cohort of LMS tumors and id...
RNA sequencing data for 170 medulloblastoma tumor samples
WGS data of medulloblastoma tumor/control pairs.
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