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TranscriptomicsDMRT6 coordinates the transition between mitotic and meiotic developmental programs during mamalian spermatogenesis
In mammals, a key transition in spermatogenesis is the exit from spermatogonial differentiation and mitotic proliferation and the entry into spermatocyte differentiation and meiosis. Although several genes that regulate this transition have been identified, how it is controlled and coordinated remai...
ORGANISM(S): Mus musculus 
2014-10-31 | E-GEOD-60440 | biostudies-arrayexpress
TranscriptomicsSexual cell fate reprogramming in the ovary by DMRT1
Transcription factors related to the insect sex determination gene Doublesex (DMRT proteins) control sex determination and/or sexual differentiation in diverse metazoans. They also are implicated in transitions between sex-determining mechanisms during vertebrate evolution. In mice Dmrt1 is required...
ORGANISM(S): Mus musculus 
2015-02-27 | E-GEOD-64960 | biostudies-arrayexpress
GenomicsChromatin Immunoprecipitation of TRA-1 in C. elegans and C. briggsae
The goal of this study is to identify and characterize sites in the C. elegans genome bound by the transcription factor TRA-1. TRA-1 ChIP-seq was performed in the following stages of animals in duplicate: 1) L2 stage of C. elegans wild-type N2 strain; 2) L3 stage of C. elegans wild-type N2 strain; 3...
ORGANISM(S): Caenorhabditis briggsae 
2013-11-04 | E-GEOD-48917 | biostudies-arrayexpress
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