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TranscriptomicsDifferential virulence gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus infection
Although dermatophytes are the most common agents of superficial mycoses in humans and animals, the molecular basis of the pathogenicity of these fungi is largely unknown. In vitro digestion of keratin by dermatophytes is associated with the secretion of multiple proteases, which are assumed to be r...
ORGANISM(S): Arthroderma benhamiae 
2010-03-04 | E-GEOD-15873 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in the human pathogenic dermatophyte Trichophyton rubrum during growth on proteins
Dermatophytes are highly specialized filamentous fungi which cause the majority of superficial mycoses in humans and animals. The high secreted proteolytic activity of these microorganisms during growth on proteins is assumed to be linked with their particular ability to exclusively infect keratiniz...
ORGANISM(S): Trichophyton rubrum 
2008-12-30 | E-GEOD-11711 | biostudies-arrayexpress
MetabolomicsOperation of a TCA cycle subnetwork in the mammalian nucleus

Nucleic acid and histone modifications critically depend on tricarboxylic acid (TCA) cycle for substrates and co-factors. Although a few TCA cycle enzymes have been reported in the nucleus, the corresponding pathways are considered to operate in mitochondria. Here, we show that a part of the...

2022-06-15 | MTBLS2235 | MetaboLights
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