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UnknownSimultaneous Visualization of R-Loops/RNA:DNA Hybrids and Replication Forks in a DNA Combing Assay.
Not available
S-EPMC11430951 | biostudies-literature
GenomicsNuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer [ChIP-seq]
Tumour cells sustain their high proliferation rate through metabolic reprogramming, whereby cellular metabolism shifts from oxidative phosphorylation to aerobic glycolysis, even under normal oxygen levels. HIF1A is a major regulator of this process but activation of HIF1A under normoxic conditions,...
ORGANISM(S): Homo sapiens 
2014-11-26 | E-GEOD-55615 | biostudies-arrayexpress
TranscriptomicsGenome-wide Mapping of ARRB1 Reveals its Role as a HIF1A Transcriptional Co-regulator and Regulator of Cellular Metabolism [expression array]
Beta-arrestin 1 (ARRB1) has been implicated in transcriptional regulation as part of protein complexes bound to chromatin. Here we investigate its effect on transcription and its potential impact on prostate cancer. We report the first genome-wide mapping of chromatin binding for ARRB1 and combine i...
ORGANISM(S): Homo sapiens 
2014-11-26 | E-GEOD-55614 | biostudies-arrayexpress
UnknownAlpha-synuclein shapes monocyte and macrophage cell biology and functions by bridging alterations of autophagy and inflammatory pathways.
Not available
S-EPMC11257978 | biostudies-literature
TranscriptomicsIntestinal label-retaining cells are secretory precursors expressing Lgr5
The epithelial lining of the small intestine is continuously renewed from a small number of stem cells including Lgr5 expressing crypt base cells that have been shown to be a rapidly cycling stem cell population in homeostasis. Alternative markers of intestinal stem cells have variously identified p...
ORGANISM(S): Mus musculus 
2013-02-27 | E-GEOD-43772 | biostudies-arrayexpress
UnknownDevelopment and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells.
Not available
S-EPMC3378185 | biostudies-literature
UnknownMetabolic glycan imaging by isonitrile-tetrazine click chemistry.
Not available
S-EPMC3743162 | biostudies-literature
UnknownTissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.
Not available
S-EPMC5884528 | biostudies-literature
UnknownMetabolic Glycan Labeling of Cancer Cells Using Variably Acetylated Monosaccharides.
Not available
S-EPMC9389531 | biostudies-literature
ProteomicsA NOVEL REGULATION OF FUMARATE HYDRATASE ACTIVITY THROUGH HISTONE DEACETYLASE 6 BINDING
Introduction: Altered metabolism is a key hallmark of tumour cells (Pavlova & Thompson, 2016) and has long been associated with relapse and resistance to treatment (Gonçalves et al., 2021; Lv et al., 2022). Recently, we identified a new role for histone deacetylase 6 (HDAC6) in the regulation of gl...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD057865 | Pride
Fumarate hydratase Regulation Histone deacetylase 6. 
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