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ProteomicsAllocryptopine alleviates IBD through modulating gut microbiota and inhibiting Cx3cl1-Cx3cr1 axis/NF-κB/apoptosis in DSS-induced mice
To explore the anti-inflammatory bowel disease (IBD) ability of allocryptiine based on label-free quantitative proteomics
ORGANISM(S): Mus Musculus 
2022-12-12 | PXD038736 |
ProteomicsThe ovarian tumor domain-containing protein 4 (OTUD4)-targeted ferroptosis inhibitor Maclekarpine E attenuates ulcerative colitis
This study aimed to evaluate the therapeutic effect of ME against UC and to elucidate its underlying molecular mechanism and potential target. ME was semi-synthesized on a gram scale via a biomimetic route. Its activity was assessed in an LPS-induced RAW264.7 macrophage model in vitro and a DSS-indu...
ORGANISM(S): Mus Musculus 
2026-01-27 | PXD073619 |
MetabolomicsThe Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe resource for the manufacture of antimicrobial feed additive for livestock. The active ...
2017-04-24 | MTBLS435 | MetaboLights
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