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GenomicsGenome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
We developed a method, ChIP-sequencing (ChIP-seq), combining chromatin immunoprecipitation (ChIP) and massively parallel sequencing to identify mammalian DNA sequences bound by transcription factors in vivo. We used ChIP-seq to map STAT1 targets in interferon stimulated and unstimulated human HeLa S...
ORGANISM(S): Homo sapiens 
2009-03-23 | E-GEOD-15353 | biostudies-arrayexpress
TranscriptomicsEffects of global system for mobile communications 1800 MHz radiofrequency electromagnetic fields on gene expression in MCF-7 cells
Despite many studies over a decade, it still remains ambiguous as to the real biological effects induced by radiofrequency electromagnetic fields (RF EMF). Epidemiological studies indicates that long-term exposure to EMF could increase the risk of breast cancer. Some reports have showed that in vitr...
ORGANISM(S): Homo sapiens 
2010-07-20 | E-GEOD-22991 | biostudies-arrayexpress
MetabolomicsAspartate potentiates tobramycin against multidrug-resistant Edwardsiella tarda through enhancing proton motive force and membrane permeability

The antibiotic susceptibility/resistance of bacteria is influenced by their metabolic states. In tobramycin-resistant Edwardsiella tarda (LTB4-RToB), a dynamic metabolic state is observed, characterized by a general reduction in most metabolites as the minimum inhibitory concentration (MIC) incre...

2025-07-31 | MTBLS12725 | MetaboLights
UnknownFeasibility and safety of 1-min sit-to-stand test in acute decompensated heart failure confirmed by lung ultrasound.
Not available
S-EPMC10030608 | biostudies-literature
ProteomicsParallel reaction monitoring (PRM) analysis for protein expression
According to a previous study on the microscopic examination of stem barks in ramie, bast fibers from different parts of stem bark showed distinct differences at the developmental level: specifically, the barks in the top part of stem (TPS) did not initiate fiber growth, whereas barks in the middle ...
ORGANISM(S): Boehmeria nivea (Chinese grass) (Urtica nivea) 
2022-02-17 | PXD026598 | Pride
Ramie Proteome Differential expression 
ProteomicsProteins interacting with SRBSDV P6 by Co-IP and mass spectrometry
Identification of proteins interacting with SRBSDV P6 by Co-IP and mass spectrometry.
ORGANISM(S): Oryza sativa (Rice) 
2025-07-16 | PXD059146 | Pride
Rice srbsdv p6 interaction 
MetabolomicsThe Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe resource for the manufacture of antimicrobial feed additive for livestock. The active ...
2017-04-24 | MTBLS435 | MetaboLights
GenomicsEvolutionary Significance of DNA Methylation in Human and Chimpanzee Brains
We compared the genome-wide patterns of DNA methylation in the brains of humans to those of our closest evolutionary relative, chimpanzees, using base-pair resolution whole-genome methylation maps of the prefrontal cortex. Our data reveal that the prefrontal cortex is the most heavily methylated am...
ORGANISM(S): Human 
2012-09-04 | E-GEOD-37202 | biostudies-arrayexpress
TranscriptomicsMicroarray of 3D cultured basal cells in the presence of Wnt3A
Adult stem cells have the ability to self-renew and to generate specialized cells. Self-renewal is dependent on extrinsic niche factors but few of those signals have been identified. We show that adult mammary glands contain a Wnt-responsive cell population that is enriched for stem cells. In cell c...
ORGANISM(S): Mus musculus 
2014-10-22 | E-GEOD-55117 | biostudies-arrayexpress
MetabolomicsMicroRNA-mediated regulation of lipid metabolism in virus-infected Emiliania huxleyi.
The interactions between Emiliania huxleyi and E. huxleyi virus (EhV) regulate marine carbon and sulfur biogeochemical cycles and play a prominent role in global climate change. As a large DNA virus, EhV has developed a novel 'virocell metabolism' model to meet its high metabolic needs. Although it ...
2024-01-16 | MTBLS5178 | MetaboLights
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