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ProteomicsA Proteogenomic Analysis of Cervical Cancer Reveals Therapeutic and Biological Insights
We performed a comprehensive proteogenomic profiling of cervical cancer (CC) tumors obtained from 139 Chinese women. This study provides a valuable public resource including proteomic, phosphoproteome, acetylproteome for researchers and clinicians to delve deeper into molecular causes of CC, and to ...
ORGANISM(S): Homo sapiens (Human) 
2024-10-09 | PXD055203 | Pride
Q-exactive hf-x Dia Phosphoproteome Tmt Q-exactive hf Timstof pro Acetylproteome Proteomic Cervical cancer 
ProteomicsThe sequence of Fully Synthetic peptides, Phosphorylated Tau181, Tau217, and Tau231 Calibrators, have been confirmed by MALDI-ISD analysis
We designed novel calibrators that include three phosphorylated Tau sites: Tau (1-22)-pT231, Tau (1-22)-pT217, and Tau (1-22)-pT181, respectively. Our synthesized peptides have various advantages compared with GSK3β-phosphorylated Tau-441. The novel fully synthesized calibrators not only improved th...
ORGANISM(S): Homo Sapiens 
2023-11-24 | PXD047248 |
ProteomicsHypothalamic malate dehydrogenase 2 (MDH2) modulates systemic glucose metabolism through oxytocin-mediated thermogenesis
Bariatric surgery improves hyperglycemia in obesity and type 2 diabetes (T2D), yet its central mechanisms remain unclear. Through cerebrospinal fluid proteomic profiling of rats, we identify reduced central malate dehydrogenase 2 (MDH2) levels that correlate with surgery-induced restoration of normo...
ORGANISM(S): Rattus Norvegicus 
2025-12-19 | PXD072275 |
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