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TranscriptomicsCCL17-expressing dendritic cells are crucial for the development of atherosclerosis
Dendritic cells (DCs) are essential for priming of immune responses. Although immune mechanisms are known to control the pathogenesis of atherosclerosis, the role of DCs remains elusive. Here we show that Ccl17 expressing mature, myeloid DCs accumulate within atherosclerotic lesions. Deletion of Ccl...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-13642 | biostudies-arrayexpress
TranscriptomicsCCL17-expressing dendritic cells are crucial for the development of atherosclerosis: T cell priming
Dendritic cells (DCs) are essential for priming of immune responses. Although immune mechanisms are known to control the pathogenesis of atherosclerosis, the role of DCs remains elusive. Here we show that Ccl17 expressing mature, myeloid DCs accumulate within atherosclerotic lesions. Deletion of Ccl...
ORGANISM(S): Mus musculus 
2011-11-01 | E-GEOD-13592 | biostudies-arrayexpress
TranscriptomicsApoptotic bodies unleash functional CXCL12 expression through microRNA-126
Apoptosis plays a pivotal role in embryogenesis and postnatal cell homeostasis, involving DNA or subcellular fragmentation, and shedding of small membranous microvesicles termed apoptotic bodies (AB). Following DNA damage, hypoxia, or vascular injury, the chemokine CXCL12 has been implicated in the ...
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-12696 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of gene expression regulation in LS174T cells transduced with either ERK-dimerization inhibitory peptide or control
Microarray analysis of gene expression regulation in LS174T cells transduced with either ERK-dimerization inhibitory peptide or control.
ORGANISM(S): Homo sapiens 
2020-02-03 | E-MTAB-8111 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of gene expression regulation in murine hearts treated with an ERK-dimerization inhibitory peptide gene therapy or control after transverse aortic constriction
This study identifies gene expression changes in murine hearts after TAC surgery and in response to gene therapy with ERK-dimerization inhibitory peptide
ORGANISM(S): Mus musculus 
2020-02-03 | E-MTAB-8110 | biostudies-arrayexpress
UnknownMolecular determinants of cardiac lymphatic dysfunction in a chronic pressure-overload model
Not available
S-SCDT-10_1038-S44321-025-00345-W | biostudies-other
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