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TranscriptomicsTranscription profiling of mouse pre-implantation development over twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst
The goal of the experiments was to profile and analyze gene activity during murine pre-implantation development. Samples were collected at twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst.
ORGANISM(S): Mus musculus 
2004-02-19 | E-MEXP-51 | biostudies-arrayexpress
TranscriptomicsVisceral Endoderm differentiation mediated by Hnf1B and is required for epiblast survival
E5.0 entails an intermediate state for primitive endoderm (PE) to visceral endoderm (VE) differentiation: a process required for proper embryonic development. Hnf1b is essential for primitive to visceral endoderm differentiation from E4.5 to E5.5. To understand development at E5.0 and pinpoint the r...
ORGANISM(S): Mus musculus 
2024-11-19 | E-MTAB-11140 | biostudies-arrayexpress
GenomicsG&T-seq: parallel sequencing of the genomes and transcriptomes of single cells
The ability to simultaneously sequence the genome and transcriptome of the same single cell offers a powerful means to dissect functional genetic heterogeneity at the cellular level. Here we describe G&T-seq, a method for separating and sequencing genomic DNA and full-length mRNA from single cells. ...
EGAS00001001204 | EGA
GenomicsEGAS00001001204-sc-20150415 - samples
Development of a method for separation and parallel sequencing of the genomes and transcriptomes of single cells.
EGAD00001001332 | EGA
TranscriptomicsTranscriptional profiling of PADI4 overexpression and inhibition in mouse embryonic stem cells
The enzymatic activity of PADI4 was investigated by overexpression and chemical inhibition to determine the effects of arginine citrullination on histone displacement, reprogramming efficiency and the maintenance of pluripotent stem cells.
ORGANISM(S): Mus musculus 
2013-11-22 | E-MTAB-1975 | biostudies-arrayexpress
ProteomicsSingle cell analysis for oocytes and early embryos
While non-mammalian embryos often rely on spatial pre-patterning, for decades it was believed that blastomeres of mouse and human embryos were developmentally equivalent. However, emerging evidence suggests early mouse and human blastomeres differ in developmental potential. Here, using multiplexed ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2025-08-10 | MSV000098778 | MassIVE
ProteomicsProteome asymmetry in mouse and human embryos before fate specification
Raw files of early-stage mouse and human blastomeres & mouse zygotes
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-05-02 | MSV000089353 | MassIVE
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