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TranscriptomicsGenome-wide profiling of E12.5 cardiomyocytes RNA expression in both heterozygous control and mutant
Congenital heart disease is among the most frequent major birth defects. Epigenetic marks are crucial for organogenesis, but their role in heart development is poorly understood. Polycomb Repressive Complex 2 (PRC2) trimethylates histone H3 at lysine 27, establishing H3K27me3 repressive epigenetic m...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-29992 | biostudies-arrayexpress
GenomicsChIP-seq of Ezh2 and H3K27me3 in E12.5 heart apex
Ezh2 and H3K27me3 binding sites in E12.5 heart apex PRC2 binding sites in wild type cardiomyocytes
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-29994 | biostudies-arrayexpress
TranscriptomicsInterrogating translating RNAs and cell-type specific gene expression using Cre-activated translating ribosome affinity purification
We characterize a Cre-activated TRAP allele (Rosa26fsTRAP) to show that endothelium-specific activation of Rosa26fsTRAP identifies endothelial cell enriched transcripts, and that cardiomyocyte-restricted TRAP is a useful means to identify genes that are differentially expressed in cardiomyocytes in ...
ORGANISM(S): Mus musculus 
2013-08-20 | E-GEOD-45152 | biostudies-arrayexpress
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