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Genomicsmerged_dataset - samples
This dataset contains merged data from the 22 Hodgkin lymphoma and 5 reactive lymph node samples, including count data and cell cluster assignments.
EGAD00001006221 | EGA
Genomicsena-DATASET-BCCA-11-12-2019-18:47:10:446-1110 - samples
Single-cell gene expression was profiled for 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes (2 replicates were performed for RLN-1). Library preparation was performed with the 10x Chromium platform (3' version 2 assay). Sequencing was performed on an Illumina NextSeq. The BAM files were gener...
EGAD00001005739 | EGA
GenomicsSingle-cell RNA sequencing of 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes
Hodgkin lymphoma (HL) is characterized by an extensively dominant tumor microenvironment (TME) composed of different types of non-cancerous immune cells with rare malignant cells. Characterization of the cellular components and their spatial relationship is crucial to understanding crosstalk and the...
EGAS00001004085 | EGA
UnknownSystemic inflammation and lymphocyte activation precede rheumatoid arthritis.
Not available
S-EPMC11565773 | biostudies-literature
UnknownProgression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation.
Not available
S-EPMC12767604 | biostudies-literature
ProteomicsPresentation of DNAJB1-PRKACA fusion neoantigens by different HLA class I alleles
Fibrolamellar carcinoma (FLC) is a liver tumor with a high mortality burden and few treatment options. A promising therapeutic vulnerability in this disease is its highly conserved driver mutation: a gene fusion between DNAJB1 and PRKACA, which is expressed in virtually all FLC tumors and could be a...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD042316 | Pride
Fusion neoantigens Hla class i Cd8 t cell Dnajb1-prkaca Fibrolamellar carcinoma 
UnknownRobust correlations across six SARS-CoV-2 serology assays detecting distinct antibody features.
Not available
S-EPMC7916820 | biostudies-literature
UnknownDNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma.
Not available
S-EPMC10983114 | biostudies-literature
UnknownImmune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations.
Not available
S-EPMC10132165 | biostudies-literature
UnknownRobust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.
Not available
S-EPMC10232372 | biostudies-literature
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