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Porphyromonas gingivalis is a gram-negative bacterium that causes destructive chronic periodontitis. In addition, this bacterium is also involved in the development of cardiovascular disease. The aim of this study was to investigate the effects of P. gingivalis infection on gene and protein expressi...
ORGANISM(S): Homo sapiens 
GSK-615 was used to treat ES2, SUM159, and A549 cells, and RNA-seq was used to look at how the compound changed gene expression in general. We aimed to predict probable TFs activated with GSK-615 treatment by focusing on the overlapping differentially expressed genes across the three cell lines impa...
ORGANISM(S): Homo sapiens 
Human primary aortic smooth muscle cells were infected with wild type (W50, 381), W50 derived gingipain mutants (E8 and K1A), or 381 derived fimbriae mutants (DPG3 and KRX178) strains of Porphyromonas gingivalis for 24 hours. The RNA was extracted from the cells and human whole genome microarray wer...
ORGANISM(S): Homo sapiens 
Pro-metastatic proteins are notably stabilized in cancer cells to promote future development, and tumors frequently repeat programs to gain invasive and dispersion capabilities. It is uncertain if unsuccessful protein degradation has an impact on cancer's metastatic programs. It is still mostly uncl...
ORGANISM(S): Homo sapiens (Human) 
2025-02-04 | PXD058467 | Pride
bulk RNA-seq data of the 5 HCC patinets. Single cell RNA seq data of these patients was under the accession number EGAD00001003337
bulk Exome-seq data of the 5 HCC patinets. Single cell RNA seq data of these patients was under the accession number EGAD00001003337
T cells isolated from peripheral blood, tumors and adjacent normal tissues from six hepatocellular carcinoma patients. SmartSeq2 and Tang2009 protocol were used to amplify RNA from single T cells. High depth enables simultaneously expression profiling and TCR assembling.
Single-cell RNA sequencing on 5063 single T cells isolated from peripheral blood, tumour and adjacent normal tissues from six hepatocellular carcinoma patients. The transcriptional properties of these individual cells, coupled with the assembled T cell receptor (TCR) sequences, were used to delineat...
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