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UnknownCombined radical and ionic approach for the enantioselective synthesis of β-functionalized amines from alcohols.
Not available
S-EPMC9881596 | biostudies-literature
UnknownAsymmetric Radical Cyclopropanation of Dehydroaminocarboxylates: Stereoselective Synthesis of Cyclopropyl α-Amino Acids.
Not available
S-EPMC8528158 | biostudies-literature
TranscriptomicsA human iPSC model of Hutchinson Gilford Progeria Syndrome reveals a possible mesenchymal stem cell defect
Hutchinson Gilford Progeria Syndrome (HGPS) is a rare, sporadic genetic disease caused by mutations in the nuclear lamin A gene. In most cases the mutation creates an efficient donor-splice site that generates an altered transcript encoding a truncated lamin A protein, progerin. In vitro studies ha...
ORGANISM(S): Homo sapiens 
2010-12-23 | E-GEOD-26093 | biostudies-arrayexpress
UnknownModeling the response to interleukin-21 to inform natural killer cell immunotherapy.
Not available
S-EPMC11792776 | biostudies-literature
GenomicsLinking genes, genomic instability and molecular subgroups in medulloblastoma
Brain tumors are the second most common pediatric cancer and carry the highest mortality rates in this age group. Medulloblastoma is the most frequent malignant brain tumor of childhood. Recent studies indicate that medulloblastoma comprises at least four sub-entities (SHH-signaling, WNT-signali...
EGAS00001000085 | EGA
UnknownBRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma.
Not available
S-EPMC4356711 | biostudies-literature
TranscriptomicsThe IRE1α-XBP1 Pathway of the Unfolded Protein Response is Required for Adipogenesis
Signaling cascades during adipogenesis culminate in the expression of two essential adipogenic factors, PPARγ and C/EBPα. Here we demonstrate that the IRE1α-XBP1 pathway, the most conserved branch of the unfolded protein response (UPR), is indispensable for adipogenesis. Indeed, XBP1-deficient ...
ORGANISM(S): Mus musculus 
2010-06-19 | E-GEOD-15771 | biostudies-arrayexpress
UnknownDoes seasonality affect snoring? A study based on international data from the past decade.
Not available
S-EPMC9552723 | biostudies-literature
UnknownstGCL: a versatile cross-modality fusion method based on multi-modal graph contrastive learning for spatial transcriptomics.
Not available
S-EPMC12924433 | biostudies-literature
TranscriptomicsmiR-193b Regulates Mcl-1 in Melanoma
MicroRNAs (miRNAs) have important roles in gene regulation. Dysregulation of miRNAs has been associated with tumorigenesis. Recent studies suggest miR-193b is a tumor suppressor gene. In a previous study, we reported that miR-193b represses cell proliferation and regulates cyclin D1 (CCND1) in melan...
ORGANISM(S): Homo sapiens 
2010-10-30 | E-GEOD-24996 | biostudies-arrayexpress
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