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ProteomicsProteomic analysis revealed the important role of vimentin in human cervical carcinoma HeLa cells treated with gambogic acid
Gambogic acid (GA) is an anti-cancer agent in phase Ⅱb clinical trial in China. In HeLa cells, GA inhibited cell proliferation, induced cell cycle arrest at G2/M phase and apoptosis, as showed by results of MTT assay and flow cytometric analysis. Possible target-related proteins of GA were searched ...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002975 | Pride
Anti-cancer Proteomics Gambogic acid Vimentin 
ProteomicsProteomic analysis revealed the important role of vimentin in human cervical carcinoma HeLa cells treated with gambogic acid
Gambogic acid (GA) is an anti-cancer agent in phase Ⅱb clinical trial in China. In HeLa cells, GA inhibited cell proliferation, induced cell cycle arrest at G2/M phase and apoptosis, as showed by results of MTT assay and flow cytometric analysis. Possible target-related proteins of GA were searched ...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002985 | Pride
Anti-cancer Proteomics Gambogic acid Vimentin 
MetabolomicsIdentifying metabolic alterations associated with coral growth anomalies using 1H NMR metabolomics
Coral growth anomalies (GAs) are tumor-like protrusions that are detrimental to coral health, impacting both the coral skeleton and soft tissues. These lesions are increasingly found throughout the tropics and are commonly associated with high human population density, yet little is known about the ...
2021-06-15 | MTBLS2424 | MetaboLights
MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
UnknownGenetic polymorphisms of long non-coding RNA GAS5 predict platinum-based concurrent chemoradiotherapy response in nasopharyngeal carcinoma patients.
Not available
S-EPMC5617505 | biostudies-literature
UnknownCloning a novel reduced-height (Rht) gene TaOSCA1.4 from a QTL in wheat.
Not available
S-EPMC11137288 | biostudies-literature
UnknownChemoselective Oxyfunctionalization of Functionalized Benzylic Compounds with a Manganese Catalyst.
Not available
S-EPMC9400980 | biostudies-literature
UnknownInteraction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma.
Not available
S-EPMC10008329 | biostudies-literature
UnknownPRDM1 Is a Key Regulator of the NKT-cell Central Memory Program and Effector Function.
Not available
S-EPMC11962401 | biostudies-literature
MetabolomicsDeciphering the metabolic perturbation in hepatic alveolar echinococcosis: a 1H NMR-based metabolomics study

BACKGROUND: Hepatic alveolar echinococcosis (HAE) is caused by the growth of Echinococcus multilocularis larvae in the liver. It is a chronic and potentially lethal parasitic disease. Early stage diagnosis for this disease is currently not available due to its long asymptomatic ...

2021-08-03 | MTBLS981 | MetaboLights
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