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TranscriptomicsThe histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
Recent studies have identified a Lys 27-to-methionine (K27M) mutation at one allele of H3F3A, one of the two genes encoding histone H3 variant H3.3, in 60% of high-grade pediatric glioma cases. The median survival of this group of patients after diagnosis is ∼1 yr. Here we show that the levels of H3...
ORGANISM(S): Homo sapiens 
2014-09-20 | E-GEOD-61586 | biostudies-arrayexpress
TranscriptomicsSmall non-coding RNA expression in murine germ cells
In order to monitor the changes in small RNAs expression during mouse spermatogenesis. Type A spermatogonia, pachytene spermatocytes and round spermatids were isolated following collagenase treatment of testes and trypsin digestion of isolated seminiferous tubules using unit gravity sedimentation in...
ORGANISM(S): Mus musculus 
2011-06-10 | E-GEOD-24822 | biostudies-arrayexpress
UnknownAssociation between life-ever gallstones and depressive symptoms in U.S. adults: a cross-sectional study.
Not available
S-EPMC11325026 | biostudies-literature
GenomicsPharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma [ChIP-seq]
ChIP-Seq analysis of a pediatric human diffuse intrinsic pontine glioma (DIPG) cell line SF8628, harboring the K27M mutation. Goal was to obtain quantitative estimates of K27me3 immunoprecipitation change between vehicle-treated SF8628 cells [dimethyl sulfoxide, (DMSO)] and SF8628 cells incubated wi...
ORGANISM(S): Homo sapiens 
2014-07-20 | E-GEOD-59496 | biostudies-arrayexpress
ProteomicsComparative proteomic analysis of porcine serum between experimental and control groups
This project contains LC-MS/MS-based proteomic data generated from porcine serum samples. Protein identification and quantitative analyses were performed to characterize the serum proteome and investigate differential protein expression among experimental groups.
ORGANISM(S): Sus Scrofa Domesticus 
2026-06-22 | PXD079982 |
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