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While the molecular mechanisms mediating submergence tolerance have been extensively studied, those underpinning age-dependent resilience remain poorly characterized. In Arabidopsis thaliana, submergence elicits a leaf-age dependent phenotype in which senescence and death progress across an age grad...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-08-14 | PXD067068 | Pride
Flooded plants experience impaired gas diffusion underwater, leading to oxygen deprivation (hypoxia) stress. The volatile plant hormone ethylene is rapidly trapped in submerged plant cells and is instrumental for enhanced metabolic hypoxia acclimation. However, the precise mechanisms underpinning et...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-12-19 | PXD031138 | Pride
According to the /N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thaliana E3 ligase, PROTEOLYSIS6 (PRT6). Here, we undertook a quantitative proteomics study of N-end rule mutant prt6, to investigate the impact of this pathway on the etiolated seedli...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-10-27 | PXD006450 | Pride
The N-degron pathway relates the half-life of a protein to its amino terminal (Nt) residue. Following cleavage of proteins by endopeptidases, new N-t amino acids are revealed and can be recognised by different E3 ligase enzymes that target the substrate proteins for degradation via the proteasome. S...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-01-09 | PXD014238 | Pride
Camelina sativa (hereafter Camelina) has emerged as a promising platform for metabolic engineering due to its short lifecycle, high seed oil content, and amenability to transformation. Previous work has demonstrated the successful introduction of non‑native pathways for the synthesis of very long ch...
ORGANISM(S): Camelina sativa (False flax) (Myagrum sativum) 
2026-08-14 | PXD074106 | Pride
Camelina sativa (hereafter Camelina) has emerged as a promising platform for metabolic engineering due to its short lifecycle, high seed oil content, and amenability to transformation. Previous work has demonstrated the successful introduction of non‑native pathways for the synthesis of very long ch...
ORGANISM(S): Camelina sativa (False flax) (Myagrum sativum) 
2026-08-14 | PXD074097 | Pride
Protein phosphorylation is instrumental to early signaling events. Studying system-wide phosphorylation in relation to processes under investigation requires a quantitative proteomics approach. In Arabidopsis, auxin application can induce pericycle cell divisions and lateral root formation. Initiati...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2014-02-25 | PXD000177 | Pride
Data from ProteomeXchange, PXD ID: PXD001719. Experiment: TAILS_freeNt, file: TAILS_B_freeNt.msf.mgf. Published as part of Proteomics. 2015 Feb 27 . From the Abstract: {{i}} According to the Arg/N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thalia...
ORGANISM(S): Ath1 
According to the Arg/N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thaliana E3 ligase, PROTEOLYSIS6 (PRT6). Proteins can also become PRT6 substrates following post-translational arginylation by arginyltransferases ATE1 and 2. Here, we undertook a q...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2015-03-26 | PXD001719 | Pride
K-ras mutations are observed in around 40% human colorectal adenomas and carcinomas and contribute to the pathogenesis of human and rodent colorectal tumour formation. Previously, we developed and characterised a strain of transgenic mice with inducible intestinal epithelial expression of K-rasVal12...
ORGANISM(S): Mus musculus 
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