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UnknownIntegrative stemness characteristics associated with prognosis and the immune microenvironment in lung adenocarcinoma.
Not available
S-EPMC9724367 | biostudies-literature
UnknownSingle-cell transcriptomics identifies PDGFRA<sup>+</sup> progenitors orchestrating angiogenesis and periodontal tissue regeneration.
Not available
S-EPMC12289874 | biostudies-literature
ProteomicsMitochondrial Proteomics Uncovers Myeloid S100A9 Deficiency Promotes Liver Injury and Fibrosis Regression via Mitochondrial Metabolic Reprogramming of Macrophages
Macrophage-mediated inflammation has been implicated in the pathogenesis of liver fibrosis. Metabolic reprogramming involves in the transition of macrophages from a pro-inflammatory M1-phenotype toward an anti-inflammatory M2-phenotype. S100A9 is highly expressed in activated macrophages and promote...
ORGANISM(S): Mus Musculus 
2025-11-03 | PXD070260 |
ProteomicsERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
The programmed cell death protein 1 (PD-1) is an inhibitory receptor on T cells and plays an important role in promoting cancer immune evasion. While ubiquitin E3 ligases for regulating PD-1 stability have been reported, deubiquitinase (DUB) governing PD-1 homeostasis to modulate tumor immunotherapy...
ORGANISM(S): Homo Sapiens 
2023-03-17 | PXD040671 |
ProteomicsDRUSP_A novel method of super-enhanced purification of ubiquitinome
A novel approach that combines Denatured-Refolded Ubiquitinated Sample Preparation (DRUSP) with a tandem hybrid specific UBD (ThUBD) for ubiquitinomic analysis.
ORGANISM(S): Mus Musculus 
PXD055428 |
ProteomicsProteomics and phosphoproteomics reveal dysregulated kinases and associated pathway in liver fibrosis
Liver fibrosis is the initial stage of most liver diseases, and it is also a pathological process involving the liver in the late stages of many metabolic diseases. Therefore, it is important to systematically understand the pathological mechanism of liver fibrosis and seek therapeutic approaches fo...
ORGANISM(S): Mus Musculus 
2025-01-16 | PXD059906 |
ProteomicsMass spectrometry analyzed human IL-33 interaction networks under various stimulations
C-terminal HA tagged hIL-33 were ectopically expressed in HEK293T cells for 24 hours, and demonstrated with indicating stimulations (Ctrl: without stimulations, Pap: 10ug/mL papain exposure for 30min, AS: 0.5mM arsenite exposure for 1hour). Cell lysates were collected for HA-immunoprecipitation and ...
ORGANISM(S): Homo Sapiens 
2022-04-26 | PXD033460 |
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