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TranscriptomicsGenetic and transcriptome analyses of early T-cell checkpoint failure and leukemia initiation in Rag1-deficient NOD mice
Both immunodeficient and wild type NOD mice exhibit defects in control of early T-cell development in the thymus. We show that Rag1-deficient NOD mice fail to enforce both the b-selection checkpoint and an earlier T-cell commitment checkpoint, based on genome-wide genetic and transcriptome analyses....
ORGANISM(S): Mus musculus 
2013-03-07 | E-GEOD-40688 | biostudies-arrayexpress
UnknownA comprehensive benchmark of single-cell Hi-C embedding tools.
Not available
S-EPMC12521359 | biostudies-literature
UnknownRigid cationic ligands enable high-efficiency NIR-II photoluminescence in copper(i) iodide hybrid semiconductors.
Not available
S-EPMC12403025 | biostudies-literature
UnknownReticular chemistry guided precise construction of zirconium-pentacarboxylate frameworks with 5-connected Zr6 clusters.
Not available
S-EPMC10901486 | biostudies-literature
UnknownDeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution.
Not available
S-EPMC10082397 | biostudies-literature
UnknownHuman intermediate prostate cancer stem cells contribute to the initiation and development of prostate adenocarcinoma.
Not available
S-EPMC11389492 | biostudies-literature
UnknownAn interpretable machine learning model based on a quick pre-screening system enables accurate deterioration risk prediction for COVID-19.
Not available
S-EPMC8633326 | biostudies-literature
UnknownChiral Effect at Nano-Bio Interface: A Model of Chiral Gold Nanoparticle on Amylin Fibrillation.
Not available
S-EPMC6474006 | biostudies-literature
Genomicsena-DATASET-Genentech-12-07-2017-18:52:38:402-9 - samples
Massively parallel nanowell-based single-cell gene expression profiling
EGAD00001003443 | EGA
GenomicsMassively parallel nanowell-based single-cell gene expression profiling
Technological advances have enabled transcriptome characterization of cell types at the single-cell level providing new biological insights. New methods that enable simple yet high-throughput single-cell expression profiling are highly desirable. Here we report a novel nanowell-based single-cell RNA...
EGAS00001002320 | EGA
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