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UnknownCOVID-19 Vaccination Acceptance Among Healthcare Workers and Non-healthcare Workers in China: A Survey.
Background: The coronavirus pneumonia is still spreading around the world. Much progress has been made in vaccine development, and vaccination will become an inevitable trend in the fight against this pandemic. However, the public acceptance of COVID-19 vaccination still remains uncertain.
S-EPMC8364953 | biostudies-literature
Other,MultiomicsChevrette et al 2019 Insect-associated Streptomyces
Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo ...
ORGANISM(S): Pseudonocardia Kitasatospora Streptomyces Gordonia <actinomycete> 
2019-12-18 | MSV000084723 | MassIVE
UnknownValidation of a genetic risk score for atrial fibrillation: A prospective multicenter cohort study.

Background

Atrial fibrillation (AF) is the most commonly encountered arrhythmia and is associated with an elevated risk of stroke. Improving the identification of patients with the highest risk for AF to enable appropriate surveillance and treatment, if necessary, is critical to reducing AF-...
S-EPMC5849279 | biostudies-literature
UnknownFolate status in the US population 20 y after the introduction of folic acid fortification.

Background

Enriched cereal-grain products have been fortified in the United States for >20 y to improve folate status in women of reproductive age and reduce the risk of folic acid-responsive neural tube birth defects (NTDs).

Objectives

Our objectives were to assess postfortification ...
S-EPMC6821545 | biostudies-literature
UnknownParallel evolution of ancient, pleiotropic enhancers underlies butterfly wing pattern mimicry.
Color pattern mimicry in Heliconius butterflies is a classic case study of complex trait adaptation via selection on a few large effect genes. Association studies have linked color pattern variation to a handful of noncoding regions, yet the presumptive cis-regulatory elements (CREs) that con...
S-EPMC6883815 | biostudies-literature
ProteomicsHuman POP analysis - Proteomics of Uterosacral Ligament Connective Tissue from Women With and Without Pelvic Organ Prolapse
Purpose: Damage to the uterosacral ligaments is an important contributor to uterine and vaginal prolapse. The aim of this study was to identify differentially expressed proteins in the uterosacral ligaments of women with and without pelvic organ prolapse and analyze their relationships to cellular...
ORGANISM(S): Homo sapiens (Human) 
2018-12-10 | PXD011467 | Pride
Ingenuity pathway analysis  itraq analysis  pelvic organ prolapse  uterosacral ligament Reproductive system 
ProteomicsSerine ADP-ribosylation depends on HPF1
We report that serine ADPr is strictly dependent on HPF1 (histone PARylation factor 1. Quantitative proteomics revealed that serine ADPr does not occur in cells lacking HPF1. We identified three endogenous serine ADPr sites are located on the PARP-1 automodification domain. Further identification of...
ORGANISM(S): Homo sapiens (Human) 
2017-02-10 | PXD005627 | Pride
Adp-ribosylation  hpf1  parp-1  parp-2  histones  proteomics 
UnknownX chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction.
Statin drugs lower blood cholesterol levels for cardiovascular disease prevention. Women are more likely than men to experience adverse statin effects, particularly new-onset diabetes (NOD) and muscle weakness. Here we find that impaired glucose homeostasis and muscle weakness in statin-treated fema...
S-EPMC11219728 | biostudies-literature
UnknownGermline hypomorphic CARD11 mutations in severe atopic disease.
Few monogenic causes for severe manifestations of common allergic diseases have been identified. Through next-generation sequencing on a cohort of patients with severe atopic dermatitis with and without comorbid infections, we found eight individuals, from four families, with novel heterozygous muta...
S-EPMC5664152 | biostudies-literature
ProteomicsRdRp MALDI Data Set - 2022, Slavish/Rimmer
Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential Eur J Med Chem. 2023 Feb 5;247:115035. doi: 10.1016/j.ejmech.2022.115035. Epub 2022 Dec 22. Slavish, ...
ORGANISM(S): Influenza Virus A/california/04/2009 
2023-07-06 | MSV000092363 | MassIVE
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