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MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
UnknownOrthologs of human disease associated genes and RNAi analysis of silencing insulin receptor gene in Bombyx mori.
Not available
S-EPMC4227205 | biostudies-literature
UnknownSpatial Distribution and Fuzzy Health Risk Assessment of Trace Elements in Surface Water from Honghu Lake.
Not available
S-EPMC5615548 | biostudies-literature
UnknownComparison of Toxic Metal Distribution Characteristics and Health Risk between Cultured and Wild Fish Captured from Honghu City, China.
Not available
S-EPMC5858403 | biostudies-literature
UnknownAlgM4: A New Salt-Activated Alginate Lyase of the PL7 Family with Endolytic Activity.
Not available
S-EPMC5923407 | biostudies-literature
UnknownmiR-23b is a negative regulator of tumor suppressing PTPRG in colorectal cancer.
Not available
S-EPMC12240168 | biostudies-literature
ProteomicsGlobal-scale profiling of differential expressed lysine lactylated proteins in cerebral endothelium of cerebral ischemia-reperfusion injury rats
(i) The lactylation may play a key role in the process of ischemia-reperfusion injury in rats, and may be achieved by regulating Ca2+signaling pathway. (ii) The key proteins of Ca2+ signaling pathway, Scl25a4 (K245), Slc25a5 (K96) and Vdac1 (K20, K266), are modified by lactation, which may affect m...
ORGANISM(S): Rattus Rattus 
2022-05-31 | PXD034232 |
UnknownGeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model.
Not available
S-EPMC11615217 | biostudies-literature
ProteomicsProteomics of obstructed kidneys from patients with obstructive nephropathy and unilateral ureteral obstruction mice
Here, we performed proteomics of kidneys obtained from patients with obstructive nephropathy and healthy controls (n=11/8), or from unilateral ureteral obstruction (UUO) mice and sham mice (n=6/6). Proteomic measurement of all human kidney samples resulted in a total of 6089 proteins with an average...
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-01-08 | PXD039314 |
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