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MetabolomicsEmerging mechanisms and promising approaches in pancreatic cancer metabolism.

Pancreatic cancer is an aggressive cancer with a poor prognosis. Metabolic abnormalities are one of the hallmarks of pancreatic cancer, and pancreatic cancer cells can adapt to biosynthesis, energy intake and redox needs through metabolic reprogramming to tolerate nutrient deficiency and hypoxic ...

2025-03-26 | MTBLS12204 | MetaboLights
ProteomicsProteome of follicular Fluid from lean and overweight/obese women with PCOS and that of healthy controls
Polycystic ovary syndrome (PCOS) is typically characterized by oligo or anovulation, hyperandrogenism and polycystic ovarian morphology, affecting 5-20% of women of reproductive age [1]. It has drawn significant attention as a major cause of anovulatory infertility and the syndrome of metabolic, rep...
ORGANISM(S): Homo sapiens (Human) 
2019-10-31 | PXD013937 | Pride
Human Pcos Tmt 
ProteomicsIntegrative transcriptome and proteome analysis reveals maize responses to Fusarium verticillioides infection inside the stalks
Fusarium verticillioides (F. verticillioides) stalk rot is one of the most devastating diseases of maize that causes significant yield losses and poses potential security concerns of foods worldwide. The underlying mechanisms of maize plants regulating defense against the disease remain poorly under...
ORGANISM(S): Zea Mays 
2022-11-04 | PXD037964 |
ProteomicsSirtuin 5-mediated desuccinylation of ALDH2 alleviates mitochondrial oxidative stress following acetaminophen-induced acute liver injury
WT mice and SIRT5 knockout mice were injected with APAP by intraperitoneal injection, and liver tissue specimens were taken 24 hours later for protein succinylation modification histology analysis
ORGANISM(S): Mus Musculus 
2024-02-24 | PXD050121 |
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