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To study the relationship between microRNAs and μ-opioid receptor (MOR) signaling, we examined microRNA expression after chronic morphine or fentanyl treatment in rat primary hippocampal neurons and in mouse hippocampus. Mouse cerebellum region was also tested as a negative control to eliminate mic...
ORGANISM(S): Homo sapiens 
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
Untargeted metabolomic profiling of the gut microbiota in Andrias davidianus. Combining non-elderly and elderly cohorts, this study reveals significant alterations in gut carbohydrate metabolites during Aging, reflecting a functional erosion of microbial processing capacity as a key hallmark of vert...
2026-07-06 | MTBLS14860 | MetaboLights
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