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MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
UnknownThe anchoring method: Estimation of interviewer effects in the absence of interpenetrated sample assignment.
Not available
S-EPMC9983757 | biostudies-literature
ProteomicsHistone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity
Histone H3 monoaminylations at glutamine(Q) 5 represent an important family of epigenetic markers in neurons that play critical roles in the mediation of permissive gene expression (1, 2). We previously demonstrated that H3Q5 serotonylation(ser) and dopaminylation(dop) are catalyzed by the Transglut...
ORGANISM(S): Homo sapiens (Human) 
2024-10-10 | PXD053429 | Pride
Tgm2 Serotonylation Neural rhythmicity Histone h3 
GenomicsChIP-Seq of LET-418::3xFLAG in mixed stage early C.elegans embryos
Our aim was to identify the genome-wide direct LET-418 binding sites in early C.elegans embryos. a FLAG-tagged version of LET-418 was expressed in let-418(ts) mutants synchronised as early mixed stage embryos, and processed for ChIP followed by deep-sequencing. The obtained binding profile was compa...
ORGANISM(S): Caenorhabditis elegans 
2016-09-12 | E-MTAB-4716 | biostudies-arrayexpress
GenomicsNational Eye Institute Glaucoma Human Genetics Collaboration (NEIGHBOR) Consortium Glaucoma Genome-Wide Association Study

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238.v1.p1 | EGA
UnknownDNALONGBENCH: a benchmark suite for long-range DNA prediction tasks.
Not available
S-EPMC12627797 | biostudies-literature
UnknownBiomarker Panel for Chronic Graft-Versus-Host Disease.
Not available
S-EPMC5012688 | biostudies-literature
UnknownUsing synthetic RNA to benchmark poly(A) length inference from direct RNA sequencing.
Not available
S-EPMC12406214 | biostudies-literature
UnknownDNALongBench: A Benchmark Suite for Long-Range DNA Prediction Tasks.
Not available
S-EPMC11741265 | biostudies-literature
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-77704 | biostudies-arrayexpress
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