Tgm2 - OmicsDI

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Universitätsklinikum Münster Klinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie Vascular Inflammation and Platelets (Gebäude A1) AG Zarbock Albert-Schweitzer-Campus 1 48149 Münster Deutschland (1)

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TGM2-mediated histone serotonylation promotes HCC progression via MYC signalling pathway

TGM2 IP-MS was performed in MHCC-97H cells to screen the interactors of TGM2. 5-PT pulldown-MS was perfromed in MHCC-97H cells to identify proteins modified by serotonylation.

ORGANISM(S): Homo Sapiens

2024-12-06 | PXD058674 |

Transcription profiling of sputum samples from individuals exercise-induced bronchoconstriction (EIB).

Asthma is a heterogeneous disease. Exercise-induced bronchoconstriction (EIB) is a distinct syndrome that occurs in 30-50% of asthmatics and is characterized by high levels of pro-inflammatory eicosanoids. We identified genes differentially expressed in the airways of asthmatics with EIB relative to...

ORGANISM(S): Homo sapiens

2010-11-10 | E-GEOD-13785 | biostudies-arrayexpress

H3K4me3Q5ser ChIP-seq of H3.3 or H3.3Q5A expressing PANC-1 cells and TGM2 knockdown PANC-1 cells

H3K4me3Q5ser ChIP-seq were performed in H3.3 or H3.3Q5A expressing PANC-1 cells and TGM2 knockdown PANC-1 cells to investigate genes directly regulated by H3K4me3Q5ser.

ORGANISM(S): Homo sapiens

2025-05-08 | E-MTAB-14997 | biostudies-arrayexpress

TGM2-Mediated Histone Transglutamination is Dictated by Steric Accessibility

PRJNA817606 | ENA

Histone serotonylation promotes pancreatic cancer development via lipid metabolism remodeling

Neurotransmitter serotonin (5-hydroxytryptamine [5-HT]) has emerged to play parallel roles in both neurobiology and oncology. Apart from receptor-mediated signaling transduction pattern, serotonin can be covalently integrated into histone (the post-translational modification known as histone sero...

2025-06-13 | MTBLS12569 | MetaboLights

RNA-seq of PANC-1 cells after TGM2 KD

PRJEB80465 | ENA

Gene expression profiling by RNA-seq of SW480 and HCT116 cells after TGM2 knockdown

PRJNA540435 | ENA

Combined inhibition of MNK signaling and BET proteins reveals TGM2 as a novel vulnerability in melanoma

Melanoma is the deadliest form of skin cancer. MAPK-targeted therapies (MAPKi) and immune checkpoint inhibitors (ICI) have shown clinical benefit but are limited by resistance mechanisms that remain poorly defined. MNK1/2 inhibitors (MNKi) have shown promising effects in pre-clinical tumor models, p...

ORGANISM(S): Homo sapiens (Human)

2024-10-01 | PXD044698 | Pride

TGM2-deficient macrophages exhibited a significant upregulation of pro-inflammatory signatures.

PRJNA1378766 | ENA

TGM2: a cell surface marker in esophageal adenocarcinomas.

Not available

S-EPMC4170218 | biostudies-literature

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