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TranscriptomicsCis- and trans- regulatory divergence between progenitor species determines gene-expression novelty in Arabidopsis allopolyploids
Gene-expression divergence between species shapes morphological evolution, but the molecular basis is largely unknown. Here we show cis- and trans-regulatory elements and chromatin modifications on gene-expression diversity in genetically tractable Arabidopsis allotetraploids. In Arabidopsis thalian...
ORGANISM(S): Arabidopsis arenosa x Arabidopsis thaliana 
2012-05-31 | E-GEOD-29687 | biostudies-arrayexpress
ProteomicsProteomics analysis of blood neutrophils from WT and Wnt5 DKO mice under DSS treatment
Neutrophils are abundant innate immune cells with important roles in host defense and many inflammatory diseases. They possess plasticity and heterogenicity, which underlie their functional ambivalency; they can be beneficial or detrimental to host well-being depending on contexts. While bone marrow...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD048613 | Pride
Wnt5 Neutrophil Proteomics Dia 
ProteomicsProteomics analysis of expi293 conditioned media purified with immobilized metal affinity chromatography
Isthmin-1 (ISM1) is a recently described adipokine with insulin-like properties, reported to regulate hyperglycemia and liver steatosis. However, contrary to earlier studies, we demonstrate that highly purified ISM1 does not stimulate AKT phosphorylation in 3T3-F442A pre-adipocytes. Instead, this ac...
ORGANISM(S): Homo sapiens (Human) 
2025-04-02 | PXD062353 | Pride
Dia Proteomics Akt 
ProteomicsPhosphoproteomic analysis supporting structural basis for GABAA receptor pi activation
GABAA receptors (GABAAR) are pentameric chloride channels comprising various combinations of different subunits that are activated by γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in vertebrates. we show here that GABRP chloride channel activity and ERK signaling is directly regul...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD044482 | Pride
Phosphoproteomics Dia Gabaa receptor 
TranscriptomicsExpression data from low nitrate culture in root in maize
Nitrate is the major source of nitrogen available for many crop plants and is often the limiting factor for plant growth and agricultural productivity especially for maize. Many studies have been done identifying the transcriptome changes under low nitrate conditions. However, the microRNAs (miRNAs)...
ORGANISM(S): Zea mays subsp. mays 
2011-08-31 | E-GEOD-31231 | biostudies-arrayexpress
ProteomicsBioactive components of Mongolian medicinal Gentiana dahurica Fisch. flowers inhibit the NF-κB signaling pathway and ameliorate chronic obstructive pulmonary disease
Bioactive components of Mongolian medicinal Gentiana dahurica Fisch. flowers inhibit the NF-κB signaling pathway and ameliorate chronic obstructive pulmonary disease
ORGANISM(S): Mus Musculus 
2026-04-08 | PXD076741 |
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