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TranscriptomicsRNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation
Purpose: We find that Wnt7a-PAX6 axis determine corneal epithelial cell fate. To obtain global evidence for successful cell fate conversion, we performed gene expression profiling by RNA-seq on CECs, SECs, and LSCs after knocking down PAX6 and on SESCs transduced with PAX6 upon 3-D differentiation. ...
ORGANISM(S): Homo sapiens 
2014-07-11 | E-GEOD-54322 | biostudies-arrayexpress
UnknownEnhanced Cardiomyocyte NLRP3 Inflammasome-Mediated Pyroptosis Promotes d-Galactose-Induced Cardiac Aging.
Not available
S-EPMC11292767 | biostudies-literature
UnknownLysosomal Hydrolase Cathepsin D Non-proteolytically Modulates Dendritic Morphology in Drosophila.
Not available
S-EPMC7532236 | biostudies-literature
UnknownSerum Klotho, vitamin D, and homocysteine in combination predict the outcomes of Chinese patients with multiple system atrophy.
Not available
S-EPMC6492708 | biostudies-literature
UnknownThe noncanonical role of the protease cathepsin D as a cofilin phosphatase.
Not available
S-EPMC8249557 | biostudies-literature
TranscriptomicsNuclear Matrix Factor hnRNP U/SAF-A Exerts a Global Control of Alternative Splicing by Regulating U2 snRNP Maturation
The nuclear matrix associated hnRNP U/SAF-A protein has been implicated in diverse pathways from transcriptional regulation to telomere length control to X inactivation, but the precise mechanism underlying each of these processes has remained elusive. Here, we report hnRNP U as a regulator of SM...
ORGANISM(S): Homo sapiens 
2012-02-16 | E-GEOD-34491 | biostudies-arrayexpress
UnknownWSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination.
Not available
S-EPMC11109945 | biostudies-literature
UnknownChrysanthemum sporopollenin: A novel vaccine delivery system for nasal mucosal immunity.
Not available
S-EPMC9947463 | biostudies-literature
UnknownChromosome-scale assembly of the Dendrobium chrysotoxum genome enhances the understanding of orchid evolution.
Not available
S-EPMC8408244 | biostudies-literature
UnknownConversion therapy for initially unresectable hepatocellular carcinoma using a combination of toripalimab, lenvatinib plus TACE: real-world study.
Not available
S-EPMC9499852 | biostudies-literature
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