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GenomicsGenome-wide distribution of UHRF2 and ZNF618 in 293T cells.
We have identified ZNF618 as a novel binding partner of UHRF2. We have found that UHRF2 and ZNF618 co-localize at many genomic loci. Examination of genome-wide distribution of SFB-tagged UHRF2 and ZNF618 in 293T cells using ChIP-seq.
ORGANISM(S): Homo sapiens 
2016-05-31 | E-GEOD-80037 | biostudies-arrayexpress
ProteomicsCircuit-wide Proteomics Profiling Reveals Brain Region-specific Protein Signatures in the WKY Rats with Endogenous Depression
Major depressive disorder (MDD) is considered as a neural circuit-based polygene syndrome that is mainly triggered by genetic susceptibility and stress factors. The present study employed the Wistar Kyoto (WKY) rat as an animal model with endogenous depression to further investigate the molecular ba...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-13 | PXD029079 | Pride
Depression  wistar kyoto rats  proteomics  medial prefrontal cortex  nucleus accumbens  hippocampus 
TranscriptomicsGenome-wide comparative ChIP-seq data of CTCF and RNA-seq data in Drosophila white prepupa on Illumina Genome Analyzer
This is a dataset which comprises the following two different kinds of genomic data in Drosophila species: First, triplicate ChIP-seq data of CTCF (CCCTC binding factor) binding profiles in each of the four closely related Drosophila species : Drosophila melanogaster, Drosophila simulans, Drosophil...
ORGANISM(S): Drosophila simulans 
2012-11-08 | E-GEOD-24449 | biostudies-arrayexpress
ProteomicsSuccinylation modification provides a new sight in the treatment of immunocompromised populations with drug-resistant Aspergillus fumigatus infection
The invasive infection of Aspergillus fumigatus poses a serious threat to human health worldwide, especially in immunocompromised patients. At present, triazole drugs are the most common antifungal drugs for aspergillosis. However, due to the emergence of drug-resistant strains, the effect of triazo...
ORGANISM(S): Aspergillus Fumigatus 
2023-02-15 | PXD040137 |
TranscriptomicsExpression profiling of Drosophila testes
We performed mRNA-seq of dissected testes of multiple Drosophila species and RNAi animals mRNA seq of testis
ORGANISM(S): Drosophila yakuba 
2012-05-01 | E-GEOD-36764 | biostudies-arrayexpress
ProteomicsPost-translational modifications confer amphotericin B resistance in Candida krusei isolated from a neutropenic patient
Neutropenia is a common complication in the treatment of hematological diseases and the most common predisposing factor for invasion by fungi, such as Candida krusei. Recent studies have shown that C. krusei, a life-threatening pathogen, has developed resistance to amphotericin B (AMB). However, the...
ORGANISM(S): Pichia Kudriavzevii 
2023-02-09 | PXD039973 |
ProteomicsPTMC_A pyridinium-based strategy for bioorthogonal conjugation-assisted purification method for profiling cell surface proteome
Cell surface proteins (CSPs) are valuable targets for therapeutic agents, but achieving highly selective CSP enrichment in cellular physiology remains a technical challenge. To address this challenge, we propose a newly developed sulfo-pyridinium-ester (SPE) cross-linking probe, followed by two-step...
ORGANISM(S): Homo Sapiens 
2023-08-11 | PXD044541 |
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