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ProteomicsProteomic of Chaihu-Shugan-San (CSS), Rou Gan, and Shu Gan treat chronic unpredictable mild stress (CUMS) rat with Tandem Mass Tags
Chaihu-Shugan-San (CSS) is a classical prescription used to treat depression. According to the traditional Chinese medicine (TCM) principle, the 2 decomposed recipes in CSS exert synergistic effects, including Shu Gan (stagnated Gan-Qi dispersion) and Rou Gan (pain alleviation). However, the specifi...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD024436 | Pride
Chaihu-shugan-san Hippocampus Depression Proteomics Traditional chinese medicine 
ProteomicsAn interaction landscape of ubiquitin signaling
This project paper describes, for the first time, a global, proteome-wide interaction screening for ubiquitin signaling. Our data reveals both cell type dependent and independent diubiquitin interactions. In additon, we show that certain proteins more potently bind to K6 diubiquitin upon induction o...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-02-08 | PXD004185 | Pride
Human Mouse Ubiquitin Lc-ms/ms 
ProteomicsAn Integrative multi-omics landscape of SARS-CoVs NSP3
Proteomic analysis of SARS-CoV NSP3 expressing cells
ORGANISM(S): Homo Sapiens 
2021-11-03 | PXD023927 |
TranscriptomicsIntegration of developmental and nutritional cues determines timing of female flower opening in cucumber
The timing of flower opening is essential for pollination and thus seed production. Despite flower opening has been a long lasting topic for plant biologists, the underling molecular mechansim remains elusive. Here we used a unique cucumber line ‘6457’ that spontaneously produces super ovary wit...
ORGANISM(S): Cucumis sativus 
2016-07-25 | E-GEOD-76358 | biostudies-arrayexpress
UnknownAltruistic behaviors relieve physical pain.
Not available
S-EPMC6969495 | biostudies-literature
ProteomicsProteomic Analysis of the Interaction between Chicken Synovial Fibroblasts and Mycoplasma synoviae
Chicken synovial fibroblasts was infected without or with Mycoplasma synoviae for 48h
ORGANISM(S): Gallus Gallus 
2019-11-29 | PXD016513 |
ProteomicsProteomic analysis of Dpy19l2-deficient human globozoospermia reveals multiple molecular defects
Globozoospermia is a severe teratozoospermia characterized by round-headed spermatozoa without acrosomes, resulting in male infertility. The clinical treatment of globozoospermia involves primarily intracytoplasmic sperm injection because of the low fertilization rate. The deletion of Dpy19l2 is kno...
ORGANISM(S): Homo sapiens (Human) 
2019-08-15 | PXD012302 | Pride
Proteomics Dpy19l2 Human Globozoospermia Round-headed 
ProteomicsHipk4 is a manchette-associated protein essential for spermiogenesis
Nonobstructive azoospermia (NOA) is one of the most severe forms of male infertility, characterized by the absence of spermatozoa in the ejaculate. The etiology and genetic mechanism(s) of this disease remain largely unclear. Using Sanger sequence, we identified 12 heterozygous missense mutations an...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-02 | PXD019303 | Pride
Hipk4 Spermiogenesis Mouse 
ProteomicsSingle-cell quantitative proteomic analysis of oocyte maturation revealed high heterogeneities in human in vitro matured oocytes
In this study we investigated the protein expression patterns during human oocyte in vitro and in vivo maturation (IVO) by single-cell quantitative proteomic analysis of 36 human oocytes. Among 2,094 proteins quantified in 34 oocytes (GV: 11 oocytes, IVM: 12 oocytes, IVO: 11 oocytes), 224 were diffe...
ORGANISM(S): Homo sapiens (Human) 
2022-08-02 | PXD023366 | Pride
Human oocyte maturation Single cell proteomics 
ProteomicsThe effects of knockout TL1A on LPS-induced ARDS mice
The TNF superfamily is large, including TNF ligands (n = 19) and TNF receptors (n = 29),as determined following the completion of large-scale sequencing of the human and mouse genomes. These members not only function in immune cells but are also involved in respiratory and intestinal diseases, and s...
ORGANISM(S): Mus Musculus 
PXD039909 |
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