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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
UnknownRisk and prediction of job burnout in responding nurses to public health emergencies.
Not available
S-EPMC10792923 | biostudies-literature
TranscriptomicsCharacterizing the expression of Pan troglodytes olfactory receptor genes
We aim, among other things, to characterize olfactory receptor (OR) genes wich are differentially expressed between olfactory epithelium (OE) and other organ tissues, in chimpanzees (Pan troglodytes), and to make comparisons with human data from a previous series using the same platform. Keywords: C...
ORGANISM(S): Pan troglodytes 
2008-10-01 | E-GEOD-11156 | biostudies-arrayexpress
TranscriptomicsCharacterizing the expression of human olfactory receptor genes
We aim, among other things, to characterize olfactory receptor (OR) genes wich are differentially expressed between olfactory epithelium (OE) and other organ tissues, in humans. Six OE samples and ten non-OE samples, including two samples of the following tissues: liver, kidney, lung, testis, and he...
ORGANISM(S): Homo sapiens 
2010-06-11 | E-GEOD-5969 | biostudies-arrayexpress
TranscriptomicsReal-time quantitative PCR analysis of DZNep treated B cell Lymphoma cell line Jeko-1
Jeko-1 cells were culture with or without PRC2 inhibitor 3-deazaneplanocin A (DZNep)(1uM) for 72hrs. We used TaqManM-BM-. Human MicroRNA Array to quantitate miRNA expression profile regulated by PRC2. qPCR miRNA expression profiling.
ORGANISM(S): Homo sapiens 
2012-08-11 | E-GEOD-40019 | biostudies-arrayexpress
TranscriptomicsTime-Dependent Gene Profiling Indicates the Presence of Different Phases for Ischemia/Reperfusion Injury in Retina
The purpose of the present study was to investigate time-dependent changes in gene expression, following induction of IR in the rat retina, and to characterize the affected pathways, networks and processes. 6 biological replicates with two treatments (Sham control and Ischemia reperfusion) and 3 tim...
ORGANISM(S): Rattus norvegicus 
2013-01-24 | E-GEOD-43671 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiling of human lung at four developmental stages and lung adenocarcioma
It is gradually becoming a new aspect in research to search and explore embryo development for malignant information hidden in tumor cells. In this study, the gene expression profiles for human lungs at four developmental stages and lung adenocarcinoma (ADC) were depicted, respectively. The molecula...
ORGANISM(S): Homo sapiens 
2014-08-25 | E-GEOD-43767 | biostudies-arrayexpress
MetabolomicsLong-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers

Long-term low-dose ionizing radiation (LLIR) widely exists in human life and has been confirmed to have potential pathogenic effects on cancer and cardiovascular diseases. However, it is technically and ethically unfeasible to explore LLIR-induced phenotypic changes in the human cohort, leading t...

2022-04-07 | MTBLS3854 | MetaboLights
Proteomics,MultiomicsHs_HCC_r2
CHPP chr 1,8,20 proteome dataset using the HCC cell lines of MHCC97H and HCCLM3, part 2
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005197 | PeptideAtlas
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