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MetabolomicsUrine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
ProteomicsRelative quantitative analysis of proteome based on iTRAQ/TMT
Relative quantitative analysis of proteome based on iTRAQ/TMT.
ORGANISM(S): Homo sapiens (Human) 
2026-08-18 | PXD054529 | Pride
Itraq/tmt Quantitative analysis 
MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
ProteomicsLC-MS/MS identification of MAVS-interacting proteins
The nanoLC-MS/MS experiments were performed on a Q Exactive mass spectrometer (Thermo Scientific) in data-dependent mode, which allowed MS data acquisition at a high resolution of 70,000 (m/z 200) across an m/z range of 300–1600. The raw data from Q Exactive analysis were analyzed with Proteome Disc...
ORGANISM(S): Homo Sapiens 
2023-03-27 | PXD041140 |
UnknownErratum: SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler.
Not available
S-EPMC4496933 | biostudies-literature
ProteomicsRIPK2 in neutrophils maintains the STAT3 promoter-enhancer loops and promotes liver metastasis of colorectal cancer cells
Identification of proteins bound to the ATF3 and RelB promoters in mice by mass spectrometry
ORGANISM(S): Mus Musculus 
2025-12-13 | PXD071993 |
ProteomicsN-glycosylated LTβR increases the Th17/Treg cell ratio in liver cancer by blocking RORC ubiquitination and FOXP3 transcription
Proteins binding to PELI1 and TRAF3 were identified by protein profiling
ORGANISM(S): Mus Musculus 
2025-04-08 | PXD062760 |
TranscriptomicsTranscriptome analysis of Liangshan pig muscle development at the growth curve inflection point and asymptotic stages using digital gene expression profiling
Animal growth curves can provide essential information for animal breeders to optimize feeding and management strategies. However, the genetic mechanism underlying the phenotypic differentiation between the inflection point and asymptotic stages of the growth curve is not well characterized. Here, w...
ORGANISM(S): Sus scrofa 
2015-05-25 | E-GEOD-69113 | biostudies-arrayexpress
ProteomicsCovalent Organic Framework with Acid Precipitation Enhances Microprotein Enrichment and Discovery of Ferroptosis-Associated Microproteins
Microproteins, defined as polypeptides fewer than 100 amino acids, are encoded by small open reading frames (sORFs) and exhibit unique structural and functional characteristics. Despite their short length and recent discoveries, microproteins have already been found to play critical roles in diverse...
ORGANISM(S): Homo Sapiens 
2026-02-26 | PXD074935 |
ProteomicsGated phosphorylated proteomics of LAIR1-overexpressed and LAIR1-control in GL261 cells
The total protein in GL261 cells was extracted, part of it was taken out for protein concentration determination and SDS-PAGE detection, and the other part was taken for trypsin digestion, peptide desalting, phosphorylation modification peptide enrichment and purification, and finally 4D-Labelfree d...
ORGANISM(S): Mus Musculus 
2023-06-13 | PXD042932 |
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