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UnknownGDF11 does not rescue aging-related pathological hypertrophy.

Rationale

Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor-β super family of secreted factors. A recent study showed that reduced GDF11 blood levels with aging was associated with pathological cardiac hypertrophy (PCH) and restoring GDF11 to normal level...
S-EPMC4636963 | biostudies-literature
UnknownA Weed-Derived Hierarchical Porous Carbon with a Large Specific Surface Area for Efficient Dye and Antibiotic Removal.
Adsorption is an economical and efficient method for wastewater treatment, and its advantages are closely related to adsorbents. Herein, the Abutilon theophrasti medicus calyx (AC) was used as the precursor for producing the porous carbon adsorbent (PCAC). PCAC was prepared through carbonizat...
S-EPMC9181242 | biostudies-literature
GenomicsGene regulatory networks mediating canonical Wnt signal directed control of pluripotency and differentiation in embryo stem cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-43597 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression and opioid signaling
To study the relationship between microRNAs and μ-opioid receptor (MOR) signaling, we examined microRNA expression after chronic morphine or fentanyl treatment in rat primary hippocampal neurons and in mouse hippocampus. Mouse cerebellum region was also tested as a negative control to eliminate mic...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-14268 | biostudies-arrayexpress
UnknownIntermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice.

Background

Neuronal pyroptosis and neuroinflammation with excess microglial activation are widely involved in the early pathological process of ischemic stroke. Repetitive transcranial magnetic stimulation (rTMS), as a non-invasive neuromodulatory technique, has recently been reported to be ...
S-EPMC9188077 | biostudies-literature
ProteomicsData of chemical composition of the particles from OH-initiated oxidation of 1,3,5-trimethylbenzene
In this work, the chemical composition of the nascent particles from the oxidation reaction is measured on-line and the high mass O2-bridged bicyclic compounds in the particle phase are directly observed and determinedby using a home-made vacuum ultraviolet (VUV) photoionization aerosol mass spectro...
ORGANISM(S): Soa 
2022-02-17 | PXD030839 | Pride
3 5-trimethylbenzene  secondary organic aerosol  molecular structures  vuv photoionization aerosol mass spectrometry Particle-phase product  1 
GenomicsChIP-seq analysis of M-NM-2-catenin in mouse embryonic stem cells treated with GSK3 inhibitor CHIR99021 under serum+LIF standard condition.
The objective of this study was to identify the direct target genes of M-NM-2-catenin acting downstream of canonical Wnt signaling in mouse embryonic stem cells (ESCs).Canonical Wnt signaling supports the pluripotency of mouse ESCs but also promotes differentiation of early mammalian cell lineages. ...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-43565 | biostudies-arrayexpress
MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
ProteomicsProteomics Profile of right ventricular remodeling at compensatory stage
Proteomics Profile of right ventricular remodeling at compensatory stage (both PAB and MCT models)
ORGANISM(S): Rattus Norvegicus 
PXD057041 |
UnknownComparative Study of the Chemical Constituents and Bioactivities of the Extracts from Fruits, Leaves and Root Barks of Lycium barbarum.
The fruits, leaves and root barks of L. barbarum plant are widely used as functional foods and as ingredients in traditional Chinese prescriptions and patent medicines. They are considered to have different pharmacological activities and health benefits because of their diverse constituents. Here, t...
S-EPMC6514792 | biostudies-literature
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