Sort   by:  
 Page size 
TranscriptomicsThe tumor suppressor Rassf1a prevents mouse liver tumorigenesis and regulates levels of the oncogenic kinase Tbk1 and of beta tubulin gene expression in the liver
The tumor suppressor gene RASSF1A (Ras association domain family protein 1A) coding for a microtubule stabilizing protein is epigenetically silenced in most human cancers. As a binding partner of the kinases MST1 and MST2, the mammalian orthologues of the Drosophila Hippo kinase, RASSF1A is a potent...
ORGANISM(S): Mus musculus 
2016-05-31 | E-GEOD-73911 | biostudies-arrayexpress
TranscriptomicsGene expression profile associated with p53R2 in human cancer cells
Deregulation of the expression of p53R2, a p53-inducible homologue of the R2 subunit of ribonucleotide reductase, has been found in various human cancer tissues; however, the roles p53R2 plays in cancer progression and malignancy remain controversial. In present design, we aimed to identify changes ...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-25238 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of mouse cerebral cortical neural progenitor cells
Transcriptome analysis of neural progenitor/stem cells is limited by the lack of a reliable method for cell isolation. We have designed a genetic dual reporter strategy that can allow prospective isolation of cortical neural progenitor cells and their neuronal progeny form the same animals. These ce...
ORGANISM(S): Mus musculus 
2011-09-19 | E-GEOD-22946 | biostudies-arrayexpress
TranscriptomicsFZD7 Plays a Critical Role in Triple Negative Breast Cancer Proliferation
Breast cancer is genetically and clinically heterogeneous. Triple negative cancer (TNBC) is a subtype of breast cancer usually associated with poor outcome and lack of benefit from target therapy. A pathway analysis in a microarray study was performed using TNBC compared with non-triple negative bre...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-27447 | biostudies-arrayexpress
Sort   by:  
 Page size