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ProteomicsFunctional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Accurate chromosome segregation is coordinated by the spindle assembly checkpoint (SAC) through its effector the mitotic checkpoint complex (MCC), to inhibit the anaphase-promoting complex or cyclosome (APC/C). Cdc20 is an essential mitotic regulator since it promotes mitotic exit through activating...
ORGANISM(S): Homo sapiens (Human) 
2023-12-06 | PXD045411 | Pride
Cdc20 cry box crispr cas9 mitosis 
UnknownFluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging.
Not available
S-EPMC3056156 | biostudies-literature
UnknownEpidemiology of osteoarthritis.
Not available
S-EPMC2920533 | biostudies-literature
MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
UnknownCherry consumption and decreased risk of recurrent gout attacks.
Not available
S-EPMC3510330 | biostudies-literature
UnknownAcetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
Not available
S-EPMC9613512 | biostudies-literature
ProteomicsSelf-priming of Plk1 binding to BubR1 ensures accurate mitotic progression
Plk1 is a key mitotic kinase that localizes to distinct subcellular structures to promote accurate mitotic progression. Plk1 recruitment depends on direct interaction between polo-box domain (PBD) on Plk1 and PBD binding motif (PBD BM) on the interactors. However, recent study showed that PBD BM alo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096264 | MassIVE
UnknownThe crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.
Not available
S-EPMC11162958 | biostudies-literature
UnknownLapsed El Nino impact on Atlantic and Northwest Pacific tropical cyclone activity in 2023.
Not available
S-EPMC11306224 | biostudies-literature
UnknownPatellofemoral morphology and alignment: reference values and dose-response patterns for the relation to MRI features of patellofemoral osteoarthritis.
Not available
S-EPMC5605424 | biostudies-literature
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