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Although internal PolyA RNA modification N6-methyladenosine (m6A) plays essential roles in diverse biological processes, technology to detect precise m6A sites at transcriptome-wide scale is lacking. Here, we discovered that m6A interferes A (Adenine) – U (Uracil) or A-T (Thymidine) pairing. Based o...
ORGANISM(S): Mus musculus 
The pituitary gland exhibits sex differences in its function. Diseases associated with dysregulation of the pituitary are also sex-biased in prevalence. Previous qPCR profiling of puberty-related genes in the pituitary gland revealed increasingly sex-biased expression of genes profiled across pubert...
ORGANISM(S): Mus musculus 
It is commonly known that mammalian microRNAs guide the RNA-induced silencing complex (RISC) to target mRNAs through the seed-pairing rule. However, recent experiments by co-immunoprecipitating the argonaute proteins (AGOs), the central catalytic component of RISC, have consistently revealed extensi...
ORGANISM(S): Homo sapiens 
TurboID tags were fused to AL7 protein, and adjacent interacting proteins were enriched by biotin. The interacting proteins were identified by mass spectrometry after protein extraction, and the differences of interacting proteins before and after TMV treatment were analyzed
ORGANISM(S): Nicotiana Benthamiana 
2025-02-18 | PXD060894 |
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