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TranscriptomicsRequirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis
As a central component during Okazaki fragment maturation, flap endonuclease 1 (FEN1) removes the 5’ flap and maintains genomic stability. Here, FEN1 was cloned as a suppressor of transcriptional gene silencing (TGS) from a forward genetic screen. FEN1 is abundant in the root and shoot apical meri...
ORGANISM(S): Arabidopsis thaliana 
2016-05-28 | E-GEOD-79738 | biostudies-arrayexpress
ProteomicsThe role of Guanylate-binding protein in Ectromelia virus
RAW-264.7 cells were infected with ECTV at an MOI of 1 for 12 and 24 hours. Following cell lysis, supernatants were subjected to immunoprecipitation (IP) using a mouse GBP1-5 antibody per the manufacturer's instructions. The elution was then analyzed using mass spectrometry (MS) by Sangon Biotech
ORGANISM(S): Mus Musculus 
2023-07-25 | PXD044061 |
TranscriptomicsA Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-mediated mRNA Translation
Increasing evidence suggests that Long non-coding RNAs (LncRNAs) represent a new class of regulators of stem cells. However, the roles of LncRNAs in stem cell maintenance and myogenesis remain largely unexamined. For this study, hundreds of novel intergenic LncRNAs were identified that are expresse...
ORGANISM(S): Mus musculus 
2015-08-11 | E-GEOD-68842 | biostudies-arrayexpress
ProteomicsHost proteins interacting with EV71-VP2 were identified by mass spectrometry
EV71-VP2-MYC was extransfected into 293T cells, and 36 hours later, the cells were treated with MG132 for 12 hours. The cells were harvested, and the cell lysates were incubated with protein-G with MYC antibody overnight. The interacting proteins were analyzed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2025-01-07 | PXD059489 |
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