Sort   by:  
 Page size 
UnknownAstragaloside IV increases PDHA1 in mesenchymal stem cell exosomes to treat myocardial infarction.
Acute myocardial infarction (AMI) is a threat to health, with high morbidity and mortality, posing a challenge to the public health system. This study aimed to explore the efficacy and potential targets of Astragaloside IV (AS-IV) combined with Mesenchymal Stem Cells (MSC)-derived exosomes (Exo) in ...
S-EPMC12259979 | biostudies-literature
UnknownGenomic prediction based on preselected single-nucleotide polymorphisms from genome-wide association study and imputed whole-genome sequence data annotation for growth traits in Duroc pigs.
The use of whole-genome sequence (WGS) data is expected to improve genomic prediction (GP) power of complex traits because it may contain mutations that in strong linkage disequilibrium pattern with causal mutations. However, a few previous studies have shown no or small improvement in prediction ac...
S-EPMC10868536 | biostudies-literature
UnknownA Comparative Study of Optimizing Genomic Prediction Accuracy in Commercial Pigs.
Genomic prediction (GP), which uses genome-wide markers to estimate breeding values, is a crucial tool for accelerating genetic progress in livestock and plant breeding. The accuracy of GP depends on several factors, including the statistical model, marker density, and cross-validation strategy. Thi...
S-EPMC11988176 | biostudies-literature
UnknownFGFR2 fusion/rearrangement analysis in intrahepatic cholangiocarcinoma using DNA/RNA-based NGS and FISH.
Patients with intrahepatic cholangiocarcinoma (iCCA) harboring FGFR2 fusion/rearrangement benefit from targeted therapies, highlighting the need for reliable testing strategies to identify FGFR2 alterations. We assessed 226 iCCA cases using RNA-based NGS, DNA-based NGS, and break-apart FISH to evalu...
S-EPMC12647265 | biostudies-literature
UnknownMulti-omic characterization of allele-specific regulatory variation in hybrid pigs.
Hybrid mapping is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai pig breeds, we perform a comprehensive multi-omic characterization of regulatory variation...
S-EPMC11222378 | biostudies-literature
ProteomicsA histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation
The RDM15 genomic sequence was fused in frame to the 3xFLAG tag and 3xMYC tag, and the fused sequences were inserted into the pCambia1305 backbone and were transformed into Arabidopsis plants, respectively. A 5-g quantity of flower tissue was harvested from transgenic plants and ground in liquid nit...
ORGANISM(S): Arabidopsis Thaliana 
2021-04-01 | PXD025147 |
UnknownEfficacy of acupuncture as an adjunctive treatment to patients with stable COPD: a multicenter, randomized, sham-controlled trial protocol.

Background

Chronic obstructive pulmonary disease (COPD) is a common respiratory disease and the third leading cause of death worldwide. Previous evidence has shown that acupuncture may be an effective complementary alternative therapy for stable COPD. However, large-sample, rigorously design...
S-EPMC10918953 | biostudies-literature
Sort   by:  
 Page size