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GenomicsChromatin Signatures in Multipotent Human HSCs Indicate the Fate of Bivalent Genes during Differentiation
Histone modifications have been implicated in stem cell maintenance and differentiation. We have analyzed genome-wide changes in gene expression and histone modifications during differentiation of multipotent human primary hematopoietic stem cells/progenitor cells (HSCs/HPCs) into erythrocyte precur...
ORGANISM(S): Homo sapiens 
2009-01-09 | E-GEOD-12646 | biostudies-arrayexpress
UnknownLuminescence Properties and Mechanisms of CuI Thin Films Fabricated by Vapor Iodization of Copper Films.
Not available
S-EPMC5456966 | biostudies-literature
Genomicsc-Myc is a universal amplifier of gene expression
This SuperSeries is composed of the following subset Series: GSE37222: c-Myc is a universal amplifier of gene expression [Microarray] GSE37229: c-Myc is a universal amplifier of gene expression [ChIP-Seq] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-37230 | biostudies-arrayexpress
GenomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis [ChIP-Seq]
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39538 | biostudies-arrayexpress
TranscriptomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39229 | biostudies-arrayexpress
Genomicsc-Myc is a universal amplifier of gene expression [ChIP-Seq]
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism and differentiation at the cellular, tissue or organismal levels via regulation of numerous target genes. In part due to the incomplete inventory and functional accounting of ...
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-37229 | biostudies-arrayexpress
ProteomicsThe crosstalk between CRL5 and APC/C E3 ligases regulates metastasis and chemo-sensitivity of cancer cells
Cullin-RING ligases (CRLs) and the anaphase-promoting complex/cyclosome (APC/C) are two major multi-subunit ubiquitin ligases essential for protein homeostasis. The underlying mechanism and biological consequence of their crosstalk remain elusive. Here, we employed tandem affinity purification follo...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD068961 | Pride
Cul5  apc11  neddylation  metastasis  chemo-sensitivity 
Transcriptomicsc-Myc is a universal amplifier of gene expression [Microarray]
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism and differentiation at the cellular, tissue or organismal levels via regulation of numerous target genes. In part due to the incomplete inventory and functional accounting of ...
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-37222 | biostudies-arrayexpress
ProteomicsSecretome profiling of Cryptosporidium sporozoites in the initial interaction processes with host epithelial cells
Sporozoites secrete proteins which can help them adhere to/invade host cells during gliding motility on the surface of host cells. Currently, the composition of secreted proteins of C. parvum during adhesion/invasion of host cells is not fully understood. In this study, TMT labeled quantitative prot...
ORGANISM(S): Homo sapiens (Human) Limnobaculum parvum 
2025-11-17 | PXD028969 | Pride
Secrete proteins Cryptospordium Sporozoites 
UnknownComparative Effects of the Single and Binary Fermentations of <i>Latilactobacillus sakei</i> and <i>Staphylococcus carnosus</i> on the Growth and Metabolomic Profiles of Fermented Beef Sausages.
Not available
S-EPMC12299760 | biostudies-literature
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