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UnknownImpact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials.
Not available
S-EPMC4737863 | biostudies-literature
MetabolomicsTranscriptomic and Metabolomics Profiling of Phage–Host Interactions between Phage PaP1 and Pseudomonas aeruginosa
The basic biology of bacteriophage–host interactions has attracted increasing attention due to a renewed interest in the therapeutic potential of bacteriophages. In addition, knowledge of the host pathways inhibited by phage may provide clues to novel drug targets. However, the effect of phage on ba...
2018-05-03 | MTBLS431 | MetaboLights
ProteomicsActivity-based sensing reveals elevated labile copper promotes liver aging via hepatic ALDH1A1 depletion
Oxidative stress plays a key role in aging and related diseases, including neurodegeneration, cancer, and organ failure. Copper (Cu), a redox-active metal ion, generates reactive oxygen species (ROS), and its dysregulation contributes to aging. Here, we develop activity-based imaging probes for the ...
ORGANISM(S): Mus Musculus (mouse) 
2025-01-16 | PXD059736 | JPOST Repository
TranscriptomicsGene expression profiling of oral squamous cell carcinoma (OSCC)
OSCC is associated with substantial mortality and morbidity. To identify potential biomarkers for the early detection of invasive OSCC, we compared the gene expressions of OSCC, oral dysplasia, and normal oral tissue from patients without oral cancer or preneoplastic oral lesions (controls). Results...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-30784 | biostudies-arrayexpress
ProteomicsQuantification of HER2 by Immunopeptide Enrichment and Targeted Mass Spectrometry in Formalin-Fixed Paraffin-Embedded (FFPE) and Frozen Breast Cancer Tissues
Background: Conventional HER2-targeting therapies improve outcomes for patients with HER2-positive breast cancer (BC), defined as tumors showing HER2 protein overexpression by an immunohistochemistry (IHC) assay and/or ERBB2 gene amplification determined by in situ hybridization (ISH). Emerging HER2...
ORGANISM(S): Homo Sapiens 
2021-07-07 | PXD021893 | panorama
GenomicsSNP6_dataset_control - samples
Control samples using SNP Array 6.0
EGAD00010000504 | EGA
Genomicsena-DATASET-BCCA-07-08-2014-18:03:45:054-88 - samples
High-grade serous ovarian cancer (HGSC) is characterized by poor outcome, often attributed to emergence of treatment-resistant sub-clones. We sought to measure the degree of genomic diversity within primary, untreated HGSC to examine the natural state of tumor evolution prior to therapy. We performe...
EGAD00001000974 | EGA
GenomicsSNP6_dataset_case - samples
Case samples using SNP Array 6.0
EGAD00010000502 | EGA
Genomicsena-DATASET-BCCA-13-08-2014-00:21:04:605-267 - samples
Multi-region whole genome sequencing of an high grade serous ovarian carcinoma sample for characterization of genomic intra-tumoural heterogeneity.
EGAD00001000978 | EGA
GenomicsU133_2_dataset_case - samples
Case samples using U133 Plus 2.0 Array
EGAD00010000500 | EGA
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